Design and prototyping of a magnetically and hydrodynamically suspended blood pump via multiobjective optimization.

Cardiovascular diseases remain a leading cause of mortality worldwide, making blood pumps or Ventricular Assist Devices essential in cardiac care. In this study, a bespoke motorpump system was designed, and by optimizing the impeller geometry across fifteen design parameters, hydraulic efficiency was enhanced while hemolysis risk was reduced. A set of 290 simulations was performed using a Design of Experiments approach, leading to the development of advanced Response Surface Models via Kriging and Genetic Aggregation. Subsequently, a Multi-Objective Genetic Algorithm was employed to maximize outlet pressure and minimize shear stress simultaneously. Among these methods, Genetic Aggregation ultimately outperformed Kriging in the final optimization phase, achieving an 11% increase in outlet pressure and a 23% reduction in mean scalar shear stress relative to the baseline. Our findings underscore the importance of managing multiple geometric factors concurrently for substantial improvements in pump performance. Building on these optimized hydraulic conditions, we introduced a magnetically levitated motor that integrates seamlessly with the pump, dispensing with mechanical bearings. The rotor remains stably suspended by hydrodynamic and magnetic forces, reducing frictional losses and prolonging the device's lifespan. This magnetically-levitated design eliminates bearings and lowers friction, suiting medical and pharmaceutical uses.