Evidence map›Paper›PMID 40681464›Full record

ArticleBlood transfusion = Trasfusione del sangue

Surveillance of blood donors detects an exceptional Parvovirus B19 outbreak in Switzerland in 2023/2024.

Mauro Serricchio, Peter Gowland, Nadja Widmer, Martin Stolz, Sophie Waldvogel, Jutta Thierbach, Andreas Buser, Franziska Suter-Riniker, Christoph Niederhauser

Abstract read
In one paragraph

Article in Blood transfusion = Trasfusione del sangue. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mauro SerricchioInterregional Blood Transfusion SRC, Bern, Switzerland.
Peter GowlandInterregional Blood Transfusion SRC, Bern, Switzerland.
Nadja WidmerInterregional Blood Transfusion SRC, Bern, Switzerland.
Martin StolzInterregional Blood Transfusion SRC, Bern, Switzerland.
Sophie WaldvogelBlood Transfusion Service SRC, Geneva, Switzerland.
Jutta ThierbachBlood Transfusion Service SRC Nordostschweiz, St. Gallen, Switzerland.
Andreas BuserBlood Transfusion Service SRC Beider Basel, Basel, Switzerland.
Franziska Suter-RinikerInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Christoph NiederhauserInterregional Blood Transfusion SRC, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman Parvovirus B19 is a common human pathogen that causes fifth disease that can be severe for immunocompromised people and unborn children. Blood donations are routinely screened for the presence of Parvovirus B19 DNA to release plasma for the fractionation industry. MATERIALS AND

methodsVoluntary, unremunerated blood donations from six regions of Switzerland were tested by Interregional Blood Transfusion Swiss Red Cross since 2008. Individual blood donations with viral titers exceeding 10

resultsFrom 2008 until September 2024, 2,789,113 blood donations were tested for the presence of Parvovirus B19 DNA, of which 271 were considered positive. Two small outbreaks in the years 2013 and 2017 and an unprecedented massive outbreak in winter/spring 2023/2024 were detected. The incidence in the 2023/2024 outbreak was 15.1 per 10,000 donations and thus about ten times higher than in the previous outbreaks with 1.6 and 1.2 positive cases per 10,000 donations, respectively. Of the genotyped cases from the 2023/2024 outbreak all were caused by Parvovirus B19 of genotype 1a2. Viral titers reached maximum values of 3×10 DISCUSSION: Similar to the situation in other European countries, Switzerland was struck with an unprecedented Parvovirus B19 outbreak in 2023/2024. The outbreak follows a two-year stretch with no positive Parvovirus B19 cases. It is likely that the measures implemented in 2020 to confine the spread of SARS-CoV-2 had a strong impact on other infectious diseases like Parvovirus B19.

Indexed as

Blood DonorsDisease OutbreaksParvoviridae InfectionsParvovirus B19, HumanAdultDNA, ViralFemaleHumansMaleMiddle AgedSwitzerlandDNA, Viral

Identifiers

PMID40681464
PMCPMC12591933

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.