Evidence map›Paper›PMID 40681256›Full record

ArticleJACC. Case reports2025

Myocardial Bridging With Left Ventricular Hypertrophy: A Case of Exercise-Induced Cardiac Arrest With Coronary Spasm.

Takumi Toya, Kaoru Naito, Tsukasa Urushima, Masami Goda, Mikio Takatoo, Shinichiro Shimura, Yuji Nagatomo, Shigeyuki Ozaki, Takeshi Adachi

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Myocardial Bridging and Cardiac Arrest.JACC. Case reports · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takumi ToyaDivision of Cardiology, National Defense Medical College, Tokorozawa, Saitama, Japan; Department of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan. Electronic address: tyt0725@gmail.com.
Kaoru NaitoDivision of Cardiology, National Defense Medical College, Tokorozawa, Saitama, Japan.
Tsukasa UrushimaDivision of Cardiology, National Defense Medical College, Tokorozawa, Saitama, Japan.
Masami GodaDivision of Cardiovascular Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.
Mikio TakatooDivision of Cardiovascular Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.
Shinichiro ShimuraDivision of Cardiovascular Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.
Yuji NagatomoDivision of Cardiology, National Defense Medical College, Tokorozawa, Saitama, Japan.
Shigeyuki OzakiDivision of Cardiovascular Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.
Takeshi AdachiDivision of Cardiology, National Defense Medical College, Tokorozawa, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA 17-year-old male athlete experienced out-of-hospital cardiac arrest due to ventricular fibrillation during exercise. Myocardial bridging (MB) and vasospasm were identified as potential contributors to the event. CASE SUMMARY: Initial imaging revealed MB of the mid-left anterior descending artery embedded within hypertrophic myocardium. Physiological assessment demonstrated significant ischemia, and acetylcholine provocation testing induced epicardial spasm, confirming MB-induced ischemia with vasospasm. Fluorodeoxyglucose positron emission tomography showed increased tracer uptake, initially suggesting malignancy, but histopathology attributed this to ischemia-related metabolic changes. The patient underwent surgical unroofing with intraoperative confirmation of arterial decompression. Postoperatively, he was treated with diltiazem and bisoprolol. DISCUSSION: This case underscores the interplay between MB and vasospasm in exercise-induced cardiac arrest and highlights surgical unroofing as a definitive treatment. TAKE-HOME MESSAGES: MB can contribute to life-threatening arrhythmias, particularly when complicated by vasospasm. Surgical unroofing with targeted medical therapy may optimize outcomes.

Indexed as

coronary spasmmyocardial bridgingout-of-hospital cardiac arrest

Identifiers

PMID40681256
PMCPMC12441336

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.