Evidence map›Paper›PMID 40681250›Full record

ArticleJACC. Case reports2025

A Case of Cutaneous Kaposi Sarcoma in a Patient Post-Heart Transplantation.

Aarti Kumar, Raina Jain, Megan Y Kamath

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aarti KumarDepartment of Internal Medicine, University of California-Los Angeles, Los Angeles, California, USA.
Raina JainDepartment of Internal Medicine, University of California-Los Angeles, Los Angeles, California, USA.
Megan Y KamathDepartment of Internal Medicine, University of California-Los Angeles, Los Angeles, California, USA. Electronic address: mkamath@mednet.ucla.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough patients with solid organ transplants have a higher risk of developing Kaposi sarcoma (KS), the data on KS post-heart transplantation are sparse. CASE SUMMARY: We present a case of a 69-year-old man with a history of heart transplantation for ischemic cardiomyopathy who developed violaceous skin lesions 5 months after transplant, with a skin biopsy confirming human herpesvirus-8-positive KS. Given no extracutaneous involvement, he was managed with a modification in his immunosuppressive regimen, with initiation of sirolimus and reduction in his tacrolimus dosage, as well as with topical imiquimod and local radiation. DISCUSSION: Although KS in other solid organ transplants, namely kidney, has been well documented, guidance on how to manage KS in post-heart transplant is lacking. TAKE-HOME MESSAGE: This case illustrates that a mammalian target of rapamycin inhibitor-based immunosuppressive regimen and locoregional therapy may be an effective strategy to manage post-heart transplantation cutaneous KS.

Indexed as

cancercardiac transplantcardiomyopathy

Identifiers

PMID40681250
PMCPMC12441440

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.