ArticleJACC. Case reports2025
IgG4-Related Aortitis as a Driver of Coronary Artery Stenosis and Ischemic Cardiomyopathy.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Chest Discomfort: Could Coronary Pathology Extend Beyond Atherosclerosis?Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVasculitis and aortitis can contribute to early coronary artery stenosis, causing ischemic cardiomyopathy. CASE SUMMARY: A 45-year-old woman with recently diagnosed heart failure and no known cardiac risk factors was found to have multivessel coronary artery disease on elective angiography, prompting coronary bypass surgery, during which her aorta appeared severely inflamed with circumferential thickening, although the stenosed coronaries had no signs of atherosclerosis, and histologic examination indicated aortitis secondary to IgG4-related disease as the driver of her ischemic cardiomyopathy. DISCUSSION: IgG4-related disease manifests in a variety of organs and tissues and is a well-known cause of aortitis with potential coronary involvement, often requiring histologic evaluation for diagnosis and management. TAKE-HOME MESSAGES: Aortitis can contribute to stenosis within the proximal coronaries either via extension of the vasculitis or external compression from the aorta. In cases of aortitis and early coronary disease, IgG4-related disease and vasculitis should be considered.
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