Evidence map›Paper›PMID 40680725›Full record

ArticleCell chemical biology2025

RPL22 links ribosome biogenesis, RNA splicing, and sensitivity to RNA polymerase I inhibition.

Kenyon Weis, Omar Abdel-Wahab

Abstract read
In one paragraph

Article in Cell chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kenyon WeisMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Omar Abdel-WahabMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: abdelwao@mskcc.org.

Funding

The Memorial Sloan Kettering Cancer Center SPORE in LeukemiaP50CA254838 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Eytan Stein · 2021 to 2026
$16.8M
Understanding and Targeting Aberrant RNA Splicing in LeukemiaR35CA304457 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Omar Abdel-Wahab · 2025 to 2026
$2.0M
NCI NIH HHS P50 CA254838NCI NIH HHS R35 CA304457
6 · The paper itself

Abstract

In this issue of Cell Chemical Biology, Fan et al.

Indexed as

Enzyme InhibitorsRibosomal ProteinsRibosomesRNA Polymerase IRNA SplicingHumansEnzyme InhibitorsRibosomal ProteinsRNA Polymerase I

Identifiers

PMID40680725
PMCPMC13289822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.