Evidence map›Paper›PMID 40680400›Full record

ArticleEarly human development2025

The effectiveness of pulmonary hypertension screening in infants born preterm.

Stephanie Vachon, Rajiv Devanagondi, Andrew Dylag, Hongyue Wang, Gloria Pryhuber

Abstract read
In one paragraph

Article in Early human development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie VachonUniversity of Rochester Medical Center, Division of Neonatology, University of Rochester Medical Center, Box 651, 601 Elmwood Avenue, Rochester, NY, United States of America. Electronic address: stephanie_vachon@urmc.rochester.edu.
Rajiv DevanagondiUniversity of Rochester Medical Center, Division of Pediatric Cardiology, University of Rochester Medical Center, Box 651, 601 Elmwood Avenue, Rochester, NY, United States of America; University of Iowa Stead Family Department of Pediatrics, 200 Hawkins Dr., BT1018, Iowa City, IA 52242, United States of America.
Andrew DylagUniversity of Rochester Medical Center, Division of Neonatology, University of Rochester Medical Center, Box 651, 601 Elmwood Avenue, Rochester, NY, United States of America.
Hongyue WangUniversity of Rochester Medical Center, Division of Neonatology, University of Rochester Medical Center, Box 651, 601 Elmwood Avenue, Rochester, NY, United States of America.
Gloria PryhuberUniversity of Rochester Medical Center, Division of Neonatology, University of Rochester Medical Center, Box 651, 601 Elmwood Avenue, Rochester, NY, United States of America.

Funding

The University of Rochester's Clinical and Translational Science InstituteUL1TR002001 · NCATS · UNIVERSITY OF ROCHESTER · PI WILSON, KAREN M., ZAND, MARTIN S · 2016 to 2024
$34.6M
NCATS NIH HHS UL1 TR002001
6 · The paper itself

Abstract

objectiveTo determine if pulmonary hypertension (PH) screening in at-risk infants born preterm reduces morbidity and/or NICU length of stay. STUDY

designThis single-center retrospective cohort chart review compared infants born <32 weeks gestational age (GA) before and after the implementation of an updated PH screening guideline. Screening eligibility and PH diagnosis were determined by applying the standardized criteria to patients in both epochs. NICU and post-discharge outcomes were determined by chart review.

resultsPre- (N = 513) and post-screening (N = 544) epochs had similar gestational age and demographic characteristics. More echocardiograms were obtained in post-screening infants resulting in more PH diagnoses (11.5 % vs. 16.5 %, p = 0.02) at a younger median post-natal age [day of life 73 (28-193) vs. 55 (28-212), median and range, p = 0.01]. PH+ infants in the post-screen epoch were discharged at a younger median post-natal age [127 (49-407) vs 113.5 (46-433) days, p = 0.02] and corrected GA [43.6 (36.7-87.4) vs 41.7 (36.6-64.9) weeks, p = 0.03].

conclusionPH screening protocol with multidisciplinary team involvement may be associated with increased detection of PH in at risk infants yet a shorter NICU stay in infants with PH.

Indexed as

Hypertension, PulmonaryInfant, PrematureNeonatal ScreeningFemaleHumansInfant, NewbornIntensive Care Units, NeonatalLength of StayMaleRetrospective StudiesBronchopulmonary dysplasiaExtremely preterm infantsNeonatology

Identifiers

PMID40680400
PMCPMC12377894

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.