Evidence map›Paper›PMID 40680178›Full record

ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2025

Role of Sarcopenia in Predicting 1-Year Outcomes After Mini-invasive Surgical or Endovascular Repair of Infrarenal Abdominal Aortic Aneurysms.

Pasqualino Sirignano, David Barillà, Giulia Colonna, Chiara Pranteda, Arianna Pignataro, Carmen Emanuela Setteducati, Stefano Brizzi, Noemi Baronetto, Maurizio Taurino, Efrem Civilini

Abstract read
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Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pasqualino SirignanoVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of General and Specialistic Surgery, "Sapienza" University of Rome, Rome, 00135/00139, Italy.ORCID 0000-0002-1312-1915
David BarillàVascular and Endovascular Surgery Unit of Humanitas Clinical and Research Center-IRCCS, Rozzano Department of Biomedical Sciences, Humanitas University, Milan, 20089, Italy.
Giulia ColonnaVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, 00189, Italy.ORCID 0009-0003-4601-7297
Chiara PrantedaVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, 00189, Italy.
Arianna PignataroVascular and Endovascular Surgery Unit of Humanitas Clinical and Research Center-IRCCS, Rozzano Department of Biomedical Sciences, Humanitas University, Milan, 20089, Italy.
Carmen Emanuela SetteducatiVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, 00189, Italy.
Stefano BrizziVascular and Endovascular Surgery Unit of Humanitas Clinical and Research Center-IRCCS, Rozzano Department of Biomedical Sciences, Humanitas University, Milan, 20089, Italy.
Noemi BaronettoVascular and Endovascular Surgery Unit of Humanitas Clinical and Research Center-IRCCS, Rozzano Department of Biomedical Sciences, Humanitas University, Milan, 20089, Italy.
Maurizio TaurinoVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, 00189, Italy.
Efrem CiviliniVascular and Endovascular Surgery Unit of Humanitas Clinical and Research Center-IRCCS, Rozzano Department of Biomedical Sciences, Humanitas University, Milan, 20089, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the outcome of frail patients electively treated for abdominal aortic aneurysm (AAA) by open surgery with enhanced repair protocol (OSER) or endovascular aneurysm repair (EVAR).

designA retrospective study on frail AAA patients treated by EVAR and OSER was conducted. Patients were defined as frail if they present a normalized total psoas muscle area (nTPA) <500 mm2/m2. This study aimed to evaluate the association between sarcopenia and AAA-related as well as all-cause mortality rates. Secondary outcomes included reinterventions, operative time, blood transfusion, length of intensive care unit (ICU), and postoperative hospital stay.

resultsA total of 403 patients were included in the study, of which 122 (30.3%) had a nTPA < 500mm2/m2. Among them, 272 (67.5%) patients were treated with EVAR while 131 (32.5%) with OSER. Although EVAR was more frequently performed in sarcopenic patients than OSER (P<0.001), there were no significant differences between the 2 groups in terms of intraoperative and postoperative outcomes. Likewise, no statistically significant differences were found regarding mortality and reintervention rates at Kaplan-Meier analysis. However, sarcopenic patients undergoing OSER exhibited a significantly higher all-cause mortality rate at 1 month (P = 0.031) and cumulative follow-up (P = 0.004) compared to all other subgroups.

conclusionsThe present experience demonstrates that less invasive approaches, but surgical or endovascular, are viable for AAA patients with no significant difference in intraoperative and immediate postoperative outcomes. Nevertheless, the potential of EVAR as a preferred strategy should be considered for frail patients based on ascertained sarcopenia.

Indexed as

Aortic Aneurysm, AbdominalEndovascular ProceduresMinimally Invasive Surgical ProceduresSarcopeniaAgedAged, 80 and overBlood Vessel Prosthesis ImplantationFemaleHumansMalePostoperative ComplicationsRetrospective StudiesTreatment Outcomeabdominal aortic aneurysmendovascular aneurysm repairenhanced recoveryfrail patientsopen repairpsoas areasarcopenia

Identifiers

PMID40680178
PMCPMC12317745

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.