ReviewScience advances2025
Acoustic technologies for the orchestration of cellular functions for therapeutic applications.
Review in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Acoustofluidic cryo-EM enables in situ particle manipulation for uniform, high-quality cryo-EM specimens.Science advances · 2026Article
- A Self-Immunoregulatory Nanosensitizer for Sonodynamic Cancer Therapy.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Integrated microfluidic biosensors: shaping the future of quantitative life sciences and on-chip molecular diagnostics.Lab on a chip · 2026Review
- Acoustic separation and isolation of viruses, small extracellular vesicles and other nanoscale bioparticles.Nature protocols · 2026Review
- Space-time acoustofluidic tweezers for dynamic and selective manipulation of microparticles.Science advances · 2026Article
- Ultrasound-Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Machine learning-driven design of engineered cilia enables hybrid operations in acoustic microrobots.Nature communications · 2026Article
- Precision acoustofluidics for high-throughput mechanobiology in suspension cells.Science advances · 2026Article
- Programmable acoustofluidic engineering for creating gradient biomaterials.Science advances · 2025Article
- Enhancing cancer therapyLab on a chip · 2025Article
- Toward a transcriptomic framework for ultrasound neuromodulation: A perspective on gene expression and regional brain sensitivity.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Mechanical forces constantly stimulate cellular functions and influence their response behaviors. Similar to how an orchestra's music synchronizes an audience, acoustic technologies have emerged as precise, contact-free tools to study cellular responses. These platforms generate forces at appropriate length and frequency scales, enabling precise interactions with cells. Recent advancements highlight their potential for regulating cellular functions, revealing both therapeutic promise and the need for further biochemical exploration. This review summarizes the progress in using acoustic technologies to orchestrate cellular functions in vitro through mechanical stimulation. We first introduce the main categories of acoustic platforms and their working principles in cellular research. Subsequently, we explore the fundamental mechanisms linking acoustics to specific cellular interactions. We then review recent applications of these technologies in precisely modulating cellular functions for therapeutic purposes. Last, we discuss strategies to enhance their performance and efficacy, along with their potential integration with other biomedical tools.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.