ArticlePloS one2025
Determinants of acceptability of schistosomiasis mass drug administration among primary school children in Busega District, Northwestern Tanzania.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A community-based participatory research and community health workers-led health education strategy for schistosomiasis control among schoolchildren in Pemba Island, Zanzibar: a cluster-randomized trial.Infectious diseases of poverty · 2026Trial
- Approaches to quantifying acceptability of pharmaceutical interventions for neglected tropical diseases: A scoping review.PLoS neglected tropical diseases · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSchistosomiasis is endemic in Tanzania, with a prevalence ranging between 12.7% to 87.6%. Mass drug administration (MDA) with praziquantel is the main recommended choice of preventive treatment for the disease. Low treatment coverage rates (46.6%) in Busega District, Northwestern Tanzania which are far less than the recommended effective coverage rates of ≥ 75% could indicate low acceptability and poor uptake of MDA. This study sought to establish factors associated with acceptability of schistosomiasis mass drug administration among primary school children in Busega District.
methodsA cross-sectional study was conducted among primary school children, randomly selected from six primary schools between 6th March and 29th May 2023. A validated generic questionnaire guided by the Theoretical Framework of Acceptability was used for data collection. The outcome of the study was acceptability of MDA, and the explanatory variables were socio-demographic factors and the seven constructs of the framework such as perceived moral about taking praziquantel, understanding of intervention purpose and affective attitude. Descriptive statistics and logistic regression with robust standard errors were conducted to identify factors associated with acceptability of MDA using STATA version 15.
resultsThe study sample comprised 615 primary school children, 60.16% girls and 39.84% boys. Age distribution ranged from 10 to 17 years with a median age of 13 years. About 55.28% were found to have high acceptability of MDA. Factors significantly associated with acceptability of MDA were; perceived effectiveness (AOR = 2.52; 95%CI = 1.31-4.85; p-value = 0.006), understanding of intervention purpose (AOR = 5.51; 95%CI = 3.16-9.59; p-value<0.0001), self-efficacy (AOR = 2.04; 95% CI = 1.08-3.85; p-value = 0.029), affective attitude (AOR = 5.10; 95% CI = 2.77-9.59; p-value<0.0001), and gender (AOR = 0.59; 95% CI = 0.38-0.94; p-value = 0.027).
conclusionSlightly more than half of primary school children recorded high acceptability of MDA. However, perceived effectiveness, understanding of intervention purpose, self-efficacy, affective attitude, and gender strongly influence acceptability. This underscores the need for tailored, gender-sensitive community sensitization efforts regarding the benefits of MDA. Targeted educational campaigns and peer-led initiatives should be prioritized to increase awareness and acceptance, ultimately improving the effectiveness of the MDA program.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.