Evidence map›Paper›PMID 40679852›Full record

ArticleJournal of clinical microbiology2025

Enhancing diagnostic preparedness for H5N1: a validation study of H5 single-plex assay and detection across multiple platforms.

Yuan Chao Xue, Jennifer Bertsch, Kaylin Monacy, Carter Haynes, Natalie Williams-Bouyer, Barbara M Judy, Patrick C Newman, Thomas G Ksiazek, Lyudmyla V Marushchak, Gregory C Gray and 1 more

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuan Chao XueDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0003-3306-3596
Jennifer BertschDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Kaylin MonacyDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Carter HaynesDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Natalie Williams-BouyerDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Barbara M JudyDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Patrick C NewmanDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Thomas G KsiazekDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Lyudmyla V MarushchakDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Gregory C GrayDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Ping RenDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0002-4022-6667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing transmission of highly pathogenic avian influenza (HPAI) H5N1 from animals to humans underscores the urgent need for enhanced diagnostic capabilities in clinical microbiology laboratories. Although

Indexed as

Influenza A Virus, H5N1 SubtypeInfluenza, HumanMolecular Diagnostic TechniquesAnimalsBirdsHumansInfluenza in BirdsLimit of DetectionReal-Time Polymerase Chain ReactionSensitivity and SpecificityClade 2.3.4.4bH5N1LDTLoD

Identifiers

PMID40679852
PMCPMC12345207

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.