Evidence map›Paper›PMID 40679825›Full record

ArticleJAMA network open2025

Hypertensive Disorders of Pregnancy and Breastfeeding Among US Women.

Deanna Nardella, Maureen E Canavan, Sarah N Taylor, Mona Sharifi

Abstract read
In one paragraph

Article in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deanna NardellaDepartment of Pediatrics, Yale University School of Medicine, New Haven, Connecticut.
Maureen E CanavanYale Cancer Outcomes, Public Policy and Effectiveness Research Center, Yale School of Medicine, New Haven, Connecticut.
Sarah N TaylorDepartment of Pediatrics, Yale University School of Medicine, New Haven, Connecticut.
Mona SharifiDepartment of Pediatrics, Yale University School of Medicine, New Haven, Connecticut.

Funding

NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
NCATS NIH HHS TL1 TR001864
6 · The paper itself

Abstract

Importance: Hypertension contributes to US maternal-infant morbidity and mortality, with potential attenuation from breastfeeding. Little is known regarding breastfeeding outcomes among mother-infant dyads exposed to hypertensive disorders of pregnancy (HDP). Objective: To quantify the extent to which HDP is associated with never breastfeeding and the time to breastfeeding cessation among postpartum women in the US. Design, Setting, and Participants: This cross-sectional study used nationally representative data from the Centers for Disease Control and Prevention Pregnancy Risk Assessment Monitoring System (PRAMS). Participants included women from 43 US states, Washington, DC, and Puerto Rico who had a live birth between January 2016 and November 2022. Complete data for HDP exposure, outcomes of breastfeeding noninitiation or cessation, and all covariates were included in the analysis, performed from October to December 2024. Exposure: Self-reported high blood pressure or hypertension, preeclampsia, or eclampsia before or during pregnancy. Main Outcomes and Measures: Odds of never breastfeeding, hazard of breastfeeding cessation, and median time to breastfeeding cessation, adjusted for sociodemographic and maternal-infant health covariates. Results: Of 205 247 women (weighted number, 10 915 302), mean (SD) age was 30.0 (5.8) years; 99.0% were first-time mothers; 54.0% had private and 40.0% had Medicaid insurance; and 91.0% delivered a term infant. HDP and breastfeeding initiation were reported by approximately 17.0% and 88.0% of women, respectively. Adjusting for covariates, HDP was associated with higher odds of never breastfeeding (adjusted odds ratio, 1.11; 95% CI, 1.05-1.18), and among those who breastfed, a higher adjusted hazard of breastfeeding cessation (adjusted hazard ratio, 1.17; 95% CI, 1.14-1.21). The median time to breastfeeding cessation among those with HDP was 17 weeks shorter than among those without HDP (unadjusted median duration, 17 [IQR, 5.0 to >46.7] vs 34 [IQR, 9.0 to >46.7] weeks). Conclusions and Relevance: In this cross-sectional study representing more than 10 million US postpartum women, HDP was associated with higher odds of never breastfeeding and a higher hazard of breastfeeding cessation. Studies to understand the potential mechanisms of this association are required to develop targeted breastfeeding support strategies for individuals with HDP.

Indexed as

Breast FeedingHypertension, Pregnancy-InducedAdultCross-Sectional StudiesFemaleHumansInfant, NewbornPregnancyUnited StatesYoung Adult

Identifiers

PMID40679825
PMCPMC12274979

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.