Evidence map›Paper›PMID 40679822›Full record

ArticleACS infectious diseases2025

Netupitant Exhibits Potent Activity on

Hassan E Eldesouky, Richard M Jones, Shabber Mohammed, Enming Xing, Pui-Kai Li, David R Sherman

Abstract read
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Hassan E EldesoukyDepartment of Microbiology, University of Washington, Seattle, Washington 98109, United States.ORCID 0000-0003-4718-6087
Richard M JonesDepartment of Microbiology, University of Washington, Seattle, Washington 98109, United States.
Shabber MohammedDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Enming XingDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Pui-Kai LiDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
David R ShermanDepartment of Microbiology, University of Washington, Seattle, Washington 98109, United States.

Funding

Systems Biology CoreU19AI162598 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI ALLAND, DAVID, ELLNER, JERROLD J. · 2021 to 2025
$13.9M
Seattle Tuberculosis Research Advancement CenterP30AI168034 · NIAID · UNIVERSITY OF WASHINGTON · PI Rhea N Coler, CHETAN SESHADRI · 2022 to 2026
$6.3M
Development of novel agents to eliminate TB persistersR21AI185169 · NIAID · UNIVERSITY OF WASHINGTON · PI DAVID R SHERMAN · 2025 to 2026
$530k
NIAID NIH HHS P30 AI168034NIAID NIH HHS R21 AI185169NIAID NIH HHS U19 AI162598
6 · The paper itself

Abstract

In

Indexed as

Antitubercular AgentsMycobacterium tuberculosisAdamantaneEthylenediaminesHumansIsoniazidMicrobial Sensitivity TestsRifampinTuberculosisAdamantaneAntitubercular AgentsEthylenediaminesIsoniazidN-geranyl-N'-(2-adamantyl)ethane-1,2-diamineRifampinATPdrug tolerancenetupitantNK1 receptor antagonistpersister cellsROS

Identifiers

PMID40679822
PMCPMC12697755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.