Evidence map›Paper›PMID 40679784›Full record

ArticleCardiovascular intervention and therapeutics2025

The need for future coronary access in older medicare beneficiaries following transcatheter aortic-valve replacement.

Christopher Brown, Michael Ryan, Marcella Kelley, Christin Thompson, Candace Gunnarsson, James Hermiller

Abstract read
In one paragraph

Article in Cardiovascular intervention and therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher BrownSwedish Heart and Vascular Institute, 550 17th Ave Suite 680, Seattle, WA, 98122, USA. brownc12@gmail.com.ORCID http://orcid.org/0000-0002-0764-973X
Michael RyanMPR Consulting, Cincinnati, OH, USA.
Marcella KelleyEdwards Lifesciences, Irvine, CA, USA.
Christin ThompsonEdwards Lifesciences, Irvine, CA, USA.
Candace GunnarssonGunnarsson Consulting, Jupiter, FL, USA.
James HermillerAscension St. Vincent's Heart Center of Indiana, Indianapolis, IN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile approximately 17% of patients less than 80 years old require coronary access in the 7 years following their TAVR, the need for coronary access among older TAVR patients is unknown.

methodsWe examined the percentage of Medicare beneficiaries aged 80-90 years that require coronary access [percutaneous coronary intervention (PCI) or angiogram] in the 8 years following their TAVR using data from the Medicare 5% Standard Analytic File (2011-2021). The need for coronary access in older patients was estimated for all TAVRs, TAVR patients with and without a history of PCI, and TAVR patients with and without coronary artery disease (CAD) using time-to-event models adjusted for age, sex, race, region, ECI score, concomitant CABG, CAD, PCI, and current or recent smoker status. Multivariate log-gamma regressions were used to estimate the total cost of hospitalizations requiring coronary access post-TAVR.

resultsA total of 6845 patients met inclusion criteria. The incidence rates for undergoing PCI or angiogram at 1, 3, 5, and 8 years were 1.9%, 4.0%, 5.5%, and 6.3%, respectively. TAVR patients with PCI demonstrated higher rates of coronary intervention compared to those without PCI (10.2% vs. 6.2% at 8 years, respectively). Similarly, TAVR patients with a prior CAD diagnosis exhibited increased rates of coronary intervention compared to those without a prior CAD diagnosis (7.4% vs. 2.1% at 8 years, respectively). The mean adjusted cost of hospitalizations requiring coronary access was $30,170 [95% Confidence Interval: $27,865-$32,665].

conclusionsApproximately 6.8% of older TAVR patients require coronary access in the 8 years following their index procedure. The presence of a prior PCI or CAD diagnosis is associated with an increased requirement for subsequent coronary access.

Indexed as

Aortic Valve StenosisCoronary AngiographyCoronary Artery DiseaseMedicarePercutaneous Coronary InterventionTranscatheter Aortic Valve ReplacementAged, 80 and overFemaleHumansMaleRetrospective StudiesUnited StatesCoronary accessMedicare beneficiariesTAVR

Identifiers

PMID40679784
PMCPMC12432029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.