ArticleMagma (New York, N.Y.)2025
Myelin water imaging from accelerated 3D-GRASE acquisitions using subspace constrained reconstruction.
Article in Magma (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeQuantitative MRI markers, such as myelin water fraction (MWF) and geometric mean
methodsWe propose two techniques to undersample the 3D-GRASE acquisition and exploit the redundancy across echoes. We retrospectively undersample fully sampled data from phantom and in-vivo acquisition to test these techniques. We compared our results for mapping MWF and IET2 to a reference multi-spin-echo technique. Additionally, we compare the proposed, state-of-the-art, and reference techniques with prospectively undersampled in-vivo acquisitions.
resultsThe RMSD of the MWF in retrospectively undersampled data was worse for the proposed techniques than the state-of-the-art. However, for IET2, RMSD was similar or slightly improved. In prospectively undersampled scans, undersampling artifacts deteriorated MWF maps, but not IET2 maps, which were within 10 ms of the reference map.
conclusionOur findings suggest that exploiting redundancy across echoes does not result in additional acceleration beyond the current state-of-the-art for MWF mapping, while it is possible to accelerate beyond state-of-the-art for IET2 mapping.
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