ReviewCurrent neurology and neuroscience reports2025
The Gray Zone of Consciousness: Cognitive Motor Dissociation.
Review in Current neurology and neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07736820 (Cyprus Disorders of Consciousness - Multimodal Assessment and Prognosis Study), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cyprus Disorders of Consciousness - Multimodal Assessment and Prognosis Study: A Single-Centre Prospective Observational Cohort Study of Clinical, Biochemical, Electrophysiological and Imaging Predictors of Long-Term Outcome After Severe Traumatic Brain Injury or Haemorrhagic Stroke
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewCovert consciousness, including cognitive motor dissociation (CMD), occurs in clinically unresponsive patients with brain injury who can willfully modulate their brain activity to comply with motor imagery commands as revealed by functional magnetic resonance imaging, EEG or other technologies. In 2024, the Curing Coma Campaign conducted a gap analysis of the field of covert consciousness and CMD. This article discusses the achievements that have been made in the field since then. RECENT
findingsThree major recent achievements include epidemiological data that CMD occurs in up to 25% of unresponsive brain injury patients, the development of convenient tools for detecting CMD at the bedside, and CMD as a biomarker of cerebral reserves that may possibly be exploited pharmacologically for prognostication and rehabilitation. Although many questions remain, recent findings have paved the way for the implementation of CMD screening in clinical routine, also in resource-poor settings, for better prognostication after brain injury and possibly for therapeutic purposes.
Indexed as
Identifiers
40679720What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.