Evidence map›Paper›PMID 40679593›Full record

ArticleInternational orthopaedics2025

Can preoperative lower limb alignment angles predict necessary soft tissue release during total knee arthroplasty for varus knees? A retrospective cohort study.

Mohammad Ayati Firoozabadi, Omid Salkhori, Mohammadreza Razzaghof, Hamed Naghizadeh, Sina Aminizadeh, Zainab Saeed Hameed Almutawa, Mohammad Poursalehian, Seyed Mohammad Javad Mortazavi

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Article in International orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Mohammad Ayati FiroozabadiJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Omid SalkhoriJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mohammadreza RazzaghofJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Hamed NaghizadehJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Sina AminizadehJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Zainab Saeed Hameed AlmutawaJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad PoursalehianJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Mohammad Javad MortazaviJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran. smjmort@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA proper balance of soft tissues is essential in total knee arthroplasty (TKA) for varus knees, but assessing soft tissue tension preoperatively is challenging. This study aimed to determine whether lower limb alignment angles can predict the necessary degree of soft tissue release.

methodsA retrospective cohort study was conducted on 953 patients with varus knees (> 10°) who underwent primary TKA from 2018 to 2020. The patients' data, release stage data, and three-joint alignment radiograph parameters were extracted from the Joint Reconstruction Research Center Knee registry, focusing on variables such as age, sex, body mass index (BMI), femoral mechanical‒anatomical angle (FMAA), lateral distal femoral angle (LDFA), medial proximal tibial angle (MPTA), joint line congruent angle (JLCA), and varus angle (VA). Data analysis was performed via SPSS 26.0.

resultsThe mean age of the patients was 65.4 (43-86) years, with a predominance of females (57.9%). Findings revealed significant associations between soft tissue release and FMAA, LDFA, MPTA, JLCA, MPTA/VA, and JLCA/VA. ROC curve analysis indicated that the JLCA/VA ratio had the highest predictive accuracy (0.997). A cutoff value of 0.49 for JLCA/VA was used to predict the soft tissue release grade, with a sensitivity of 98.8% and specificity of 99.9%.

conclusionAngular parameters from three-joint alignment radiographs can effectively predict soft tissue release needed for TKA in varus knees, with the JLCA/VA being the most reliable parameter.

Indexed as

Arthroplasty, Replacement, KneeKnee JointLower ExtremityOsteoarthritis, KneeAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesExtension gap balancingFlexion gap balancingSoft tissue releaseTotal knee arthroplasty

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.