Evidence map›Paper›PMID 40679512›Full record

ReviewChirurgie (Heidelberg, Germany)2025

[Chronic anal fissure-Cremes or surgery?]

Marie Klein, Marcel Zadnikar, Lukas Marti

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Chirurgie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marie KleinKlinik für Chirurgie, Kantonsspital St. Gallen, Rorschacherstr. 95, 9007 St. Gallen, Schweiz.
Marcel ZadnikarKlinik für Chirurgie, Kantonsspital St. Gallen, Rorschacherstr. 95, 9007 St. Gallen, Schweiz.
Lukas MartiKlinik für Chirurgie, Kantonsspital St. Gallen, Rorschacherstr. 95, 9007 St. Gallen, Schweiz. lukas.marti@h-och.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An anal fissure is a painful lesion of the anal canal. The acute form often heals spontaneously and should be treated conservatively. The treatment of chronic anal fissures is the subject of many studies but the treatment recommendations of international guidelines are contradictory. Conservative treatment consists of chemical sphincterotomy using sphincter-relaxing drugs, such as calcium channel antagonists, nitrates or botulinum toxin and leads to healing in only about 50% of patients with a prolonged healing time and a high rate of recurrence. In contrast surgical treatment is much more effective. Lateral internal sphincterotomy is the most effective treatment with a success rate of >90%. Fissurectomy with a success rate of 80% is preferred in German-speaking countries due to its much lower risk of incontinence.

Indexed as

Fissure in AnoAnal CanalBotulinum ToxinsChronic DiseaseHumansSphincterotomyBotulinum ToxinsBotulinum toxinCalcium channel antagonistsFecal incontinenceFissurectomyLateral internal sphincterotomy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.