Evidence map›Paper›PMID 40679306›Full record

ArticleJournal of hospital medicine2025

The impact of a best practice advisory for shifting to oral medications: A quality improvement project.

Rebecca Y Linfield, Leon S Moskatel, Sean Carlton, Fatemeh Amrollahi, David Epstein, Amy Chang, David Svec, Jonathan H Chen, Lisa Shieh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hospital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rebecca Y LinfieldDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0002-8079-700X
Leon S MoskatelDepartment of Neurology, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0002-8596-9130
Sean CarltonDepartment of Clinical Informatics, Stanford Health Care, Palo Alto, California, USA.
Fatemeh AmrollahiDepartment of Biomedical Informatics, Department of Medicine, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0009-0009-6617-0241
David EpsteinDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0002-8541-2623
Amy ChangDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0002-1194-8222
David SvecDivision of Hospital Medicine, Department of Medicine, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0009-0002-7415-9244
Jonathan H ChenDepartment of Biomedical Informatics, Department of Medicine, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0002-4387-8740
Lisa ShiehDivision of Hospital Medicine, Department of Medicine, Stanford University, Palo Alto, California, USA.

Funding

EMERGING INFECTIOUS DISEASEST32AI007502 · NIAID · STANFORD UNIVERSITY · PI Prasanna Jagannathan, DAVID A. RELMAN · 1995 to 2026
$6.8M
NIAID NIH HHS T32 AI007502
6 · The paper itself

Abstract

We developed a Best Practice Advisory (BPA) to encourage switching from intravenous (IV) to oral (PO) formulations of antimicrobials with equal efficacy, to decrease costs and IV usage. We conducted a prospective study analyzing our BPA's effect on prescribing practices of antimicrobials in the inpatient setting of Stanford Hospital in Palo Alto, CA, over a 22-month period. Our BPA achieved a 1526/6585 (23.2%) acceptance rate and led to decreased use of IV antimicrobials, with substantial direct cost savings of at least $66,976. Future efforts will focus on expanding our BPA to non-antimicrobials given ongoing IV fluid shortages.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsPractice Guidelines as TopicPractice Patterns, Physicians'Quality ImprovementAdministration, IntravenousAdministration, OralHumansProspective StudiesAnti-Bacterial AgentsAnti-Infective Agents

Identifiers

PMID40679306
PMCPMC12904682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.