Evidence map›Paper›PMID 40679295›Full record

ArticleJournal of virology2025

Single-cell RNA sequencing reveals hemocyte heterogeneity, differentiation trajectories, and viral tropism in shrimp (

Bang Xiao, Fang Kang, Taolin Fan, Qianqian Li, ManMan Liu, Junming Pan, Jianguo He, Chaozheng Li

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bang Xiao *School of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University, Guangzhou, P. R. China.ORCID 0009-0007-8960-4220
Fang Kang *School of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University, Guangzhou, P. R. China.
Taolin FanSchool of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University, Guangzhou, P. R. China.
Qianqian LiSchool of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University, Guangzhou, P. R. China.
ManMan LiuSchool of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University, Guangzhou, P. R. China.
Junming PanSchool of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University, Guangzhou, P. R. China.
Jianguo HeSchool of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University, Guangzhou, P. R. China.ORCID 0000-0003-2460-7061
Chaozheng LiSchool of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University, Guangzhou, P. R. China.ORCID 0000-0001-7639-7831

Funding

China Postdoctoral Science Foundation 2023M743987Guangdong Basic and Applied Basic Research Foundation 2023A1515110528National Natural Science Foundation of China 32373158/32441085/31930113the Guangdong S&T programme 2024B1212060001the open competition program of top ten critical priorities of Agricultural Science and Technology Innovation for the 14th Five-Year Plan of Guangdong Province 2022SDZG01
6 · The paper itself

Abstract

Decapodiridovirus litopenaeus1 (DIV1) is a highly pathogenic virus threatening crustacean aquaculture. Hemocytes, the primary immune cells in shrimp, play crucial roles in host defense, yet their transcriptional heterogeneity and differentiation dynamics under viral infection remain poorly understood. Here, we characterize hemocyte subpopulations in

Indexed as

DicistroviridaeHemocytesPalaemonidaeAnimalsCell DifferentiationSequence Analysis, RNASingle-Cell Analysisdecapodiridovirus litopenaeus1 (DIV1)hemocyte differentiationshrimpsingle-cell RNA sequencingviral tropism

Identifiers

PMID40679295
PMCPMC12363182

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.