Evidence map›Paper›PMID 40679158›Full record

ArticleVeterinary medicine and science2025

Fibrosing Mediastinitis in a 5-Year-Old Labrador Retriever.

Kyle L Granger, Julien Guillaumin, Kurt Williams, Sarah Shropshire, Alex Ohlendorf, Kelly E Hall

Abstract readCase Reports
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kyle L GrangerDepartment of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0003-0348-9094
Julien GuillauminDepartment of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Kurt WilliamsDepartment of Biomedical Sciences and Oregon Veterinary Diagnostic Laboratory, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA.
Sarah ShropshireDepartment of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Alex OhlendorfDepartment of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Kelly E HallDepartment of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0001-5399-932X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFibrosing mediastinitis (FM) is a rare but serious condition characterized by excessive fibrous tissue proliferation in the mediastinum, often leading to compression of vital structures. Although considered benign, in people, clinical manifestations of FM can range from asymptomatic incidental findings on imaging studies to severe respiratory compromise and hemodynamic instability. While documented in people, FM has not yet been reported in dogs. CASE PRESENTATION: A 5-year-old male neutered Labrador Retriever presented with progressive respiratory distress, leading to pleural effusion and facial swelling. Thoracic radiographs revealed mediastinal mass-like structures and pleural effusion. Computed tomography demonstrated a mediastinal mass-like structure, enlarged tracheobronchial lymph nodes, multifocal narrowing of lobar bronchi and pulmonary veins and compression of the oesophagus and trachea. The dog was humanely euthanized due to poor response to empiric therapy and the owner's perception of suffering. A post-mortem examination confirmed severe chronic mediastinal inflammation with fibrosis and vasculitis consistent with fibrosing mediastinitis.

conclusionsThis report presents a unique case of FM in a dog.

Indexed as

Dog DiseasesMediastinitisSclerosisAnimalsDogsFatal OutcomeFibrosisMaleTomography, X-Ray Computedchronic inflammationfibrosing mediastinitismediastinal masspleural effusionrespiratory distress

Identifiers

PMID40679158
PMCPMC12272489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.