ReviewBiochemistry and biophysics reports2025
Endogenous Plant signals and human Health: Molecular mechanisms, ecological functions, and therapeutic Prospects.
Review in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Volatile Organic Compounds and Beyond: Chemical Diversity and Biological Activities ofMolecules (Basel, Switzerland) · 2026Review
- Noncoding RNAs and the phytochemical economy: Molecular regulators of secondary metabolism in medicinal plants.Biochemistry and biophysics reports · 2026Review
- Advances in understanding the functions and regulatory factors of secondary metabolites inPlant signaling & behavior · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endogenous plant signals, including phytohormones, secondary metabolites, and volatile organic compounds, play pivotal roles in plant growth, defense, and ecological interactions. Signals are crucial in plant responses to both biotic and abiotic stressors, as well as in the biosynthesis of therapeutic compounds. Jasmonic acid, salicylic acid, and ethylene are crucial signaling molecules that regulate internal and external communication, including herbivore defense and microbial interactions. Volatile organic compounds further enable plant-plant communication and ecological resilience. Increasing evidence links these signaling pathways to the production of compounds with antioxidant, anti-inflammatory, and anticancer properties in humans, bridging plant ecology with human health. This narrative review was conducted through integrative thematic synthesis of peer-reviewed literature published between 2015 and 2025, using databases such as PubMed, Scopus, and ScienceDirect. Articles were selected based on their relevance to the molecular mechanisms, ecological roles, and therapeutic implications of endogenous plant signals. Emphasis was placed on interdisciplinary studies spanning molecular biology, pharmacology, and systems ecology. This review explores recent advancements in plant signals' molecular and ecological roles, emphasizing their importance in sustainable agriculture, drug discovery, and functional foods. Signaling networks' complexity necessitates interdisciplinary strategies involving molecular biology, systems ecology, and pharmacology, which can be harnessed through biotechnology and systems-based research for therapeutic and ecological innovations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.