ArticleAmerican journal of ophthalmology case reports2025
Rose bengal photodynamic antimicrobial therapy combined with amniotic membrane graft for the management of infectious keratitis in a patient with keratoprosthesis.
Article in American journal of ophthalmology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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7 authors.
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Abstract
Purpose: To describe the use of Rose Bengal Photodynamic Antimicrobial Therapy (RB-PDAT) combined with amniotic membrane graft (AMG) as a novel surgical technique for infectious keratitis in a patient with Boston Keratoprosthesis (B-Kpro) type 1 Lucia. Methods: A 91-year-old woman with a history of B-Kpro type 1 Lucia implantation in both eyes presented for routine follow-up complaining of pain and redness in the left eye. Slit-lamp examination revealed a 6 mm corneal infiltrate with an epithelial defect adjacent to the optic stem. After 2 weeks of topical antimicrobial therapy without any improvement, the decision was made to perform RB-PDAT in conjunction with an AMG. The infectious keratitis resolved within 21 days. Conclusions: The combination of RB-PDAT and AMG may be considered as a surgical alternative in patients with keratoprosthesis complicated by severe infectious keratitis refractory to standard medical treatment.
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