ArticleEClinicalMedicine2025
The effects of orphanhood and lack of parental care on child vaccination: analyses of 189 cross-sectional UNICEF Multiple Indicator Cluster Surveys from 82 countries, 2005-2022.
Article in EClinicalMedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The effects of orphanhood and lack of parental care on child vaccination: analyses of 189 cross-sectional UNICEF Multiple Indicator Cluster Surveys from 82 countries, 2005-2022.EClinicalMedicine · 2025Article
- Profiling zero-dose measles-rubella children in Zambia: Insights from the 2024 post-campaign coverage survey.PLOS global public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Background: Children lacking parental protection may tend to miss out on essential services. We investigated whether orphans and children without parental care were at risk of sub-optimal vaccination. Methods: Cross-sectional analyses of 189 UNICEF Multiple Indicator Cluster Surveys from 82 predominantly low- and middle-income countries, conducted from January 1, 2005 to December 31, 2022. We used two-level logistic fixed-effects models with individual community-dwelling children aged 12-59 months nested within MICS sampling cluster to estimate the effects of orphanhood (one or both parents deceased) and lack of parental care (children residing with no biological parents) on missed vaccinations. We report the adjusted odds of being a "zero-dose" child (failure to receive any diphtheria-tetanus-pertussis-containing (DTP) vaccine doses), an under-immunised child (failure to receive three DTP doses), failure to receive any measles-containing vaccine (MCV), and failure to receive all eight basic vaccine doses. Findings: The analysis included 739,506 children of which 20.6% (n = 152,314) were zero-dose, 50.4% (n = 372,568) were under-immunised, 50.3% (n = 372,089) had not received any MCV, and 57.8% (n = 427,558) had not received all 8 basic vaccine doses. Orphans had a consistently higher risk of sub-optimal vaccination. Adjusted odds ratios were similar for all binary outcomes (zero-dose (OR Interpretation: To better support children at risk and uphold their rights, vaccination programmes should prioritise service delivery to orphans and children lacking parental care. Funding: Eunice Kennedy Shriver National Institute of Child Health and Human Development and the Canadian Institutes for Health Research.
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Registered trials
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