ReviewJournal of Taibah University Medical Sciences2025
Strategies in the development of pro-oxidant therapy for oral squamous cell carcinoma: A scoping review.
Review in Journal of Taibah University Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Oxidative Stress and its Role in Carcinogenesis.Cell biochemistry and biophysics · 2026Review
- Recent Progress on Polyphenols of Malaysian Honey and Their Molecular Mechanism Pathways in Cancer-A Comprehensive Review.International journal of molecular sciences · 2026Review
- Molecular Mechanisms in Oral Squamous Cell Carcinoma: Integrative Roles of Cancer-Associated Fibroblasts, Immune Microenvironment, and Precision Therapeutic Opportunities.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pro-oxidant therapy has gained attention as newly potential approach in combating oral cancer. However, there are lack of classification and comparative analysis on extensive literatures which focuses on the different strategies and efficacy of pro-oxidant based therapies. This review aims to investigate the development of pro-oxidant therapy in treatment of oral cancer, emphasising on the fundamental knowledge behind each method, the impacts of each pro-oxidant-based method on cancer cell lines, and the future application in clinical practices. Method: The present scoping review is carried out according to the Arksey and O'Malley framework's four-stage scoping review technique. The search was conducted from different electronic research databases such as Google Scholar, Web of Science, PubMed, and Scopus to select relevant peer-reviewed studies. The search strategy includes keywords such as "strategies" "development", "pro-oxidant", therapy", "oral"and "squamous cell carcinoma". The articles were screened, by keeping in mind the inclusion and exclusion criteria, along with assessment for eligibility. The present study is registered with Open Science Framework (OSF), followed by PRISMA-ScR guidelines to increase the relevance for decision-making. Results: 313 articles were selected by searching the literature databases, 250 were identified relevant to the present scoping review topic. Following the screening criteria, only 15 articles were included in the final review for detail analysis. Conclusions: The gathered data positively contribute to more discoveries of advanced techniques for the management of cancer with minimal toxicities to improve on treatment outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.