Evidence map›Paper›PMID 40678445›Full record

ArticleAddiction neuroscience2025

Oxytocin attenuates demand for cocaine in female rats.

Amy S Kohtz, Hannah Davies, Belle Lin, Gary Aston-Jones

Abstract read
In one paragraph

Article in Addiction neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amy S KohtzDepartment of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0002-7625-6534
Hannah DaviesBrain Health Institute, Rutgers University, Piscataway, NJ 08854, USA.
Belle LinBrain Health Institute, Rutgers University, Piscataway, NJ 08854, USA.
Gary Aston-JonesBrain Health Institute, Rutgers University, Piscataway, NJ 08854, USA.

Funding

TRAINING IN EVIRONMENTAL TOXICOLOGYT32ES007148 · NIEHS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI Lauren M Aleksunes · 1987 to 2026
$11.4M
ROLE OF OREXIN IN COCAINE DEMAND AND ADDICTIONR01DA006214 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI ASTON-JONES, GARY S. · 1989 to 2024
$6.0M
Sex Differences in AddictionR00DA045758 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI KOHTZ, AMY · 2022 to 2024
$747k
NIDA NIH HHS R00 DA045758NIDA NIH HHS R01 DA006214NIEHS NIH HHS T32 ES007148
6 · The paper itself

Abstract

There are substantial sex differences in substance use disorders (SUDs), and a key feature of SUD is pathologically high economic demand for drug. The hypothalamic neuropeptide oxytocin (OXT) is heavily implicated in the modern treatment of SUDs. Using a within-session threshold behavioral economics (BE) procedure, we quantified demand elasticity (a, inverse motivation) and free consumption (Q

Indexed as

Behavioral economicsCocaineOxytocinProgesteroneSex differences

Identifiers

PMID40678445
PMCPMC12269613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.