ArticleJHLT open2025
Chest wall strapping in a porcine model: Dynamic dysanapsis dilates airways for optimized function of the "oversized" lung.
Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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2 authors.
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Abstract
Chest-Wall-Strapping (CWS), a technique forcing the lung to operate at low volumes, is a model for an oversized lung allograft. Dynamic-dysanapsis describes airway dilation mediated by increased elastic recoil from CWS. We hypothesized that Dynamic-dysanapsis can be quantified via the Dysanapsis-Ratio, defined as the airway-size to lung-volume ratio. Farm-raised pigs (n=3) were mechanically ventilated. Stepwise CT-images throughout the lung deflation limb in control and CWS conditions were analyzed quantifying airway dimensions and lung volume. CWS (30%-reduction in lung-volume) was associated with a significant increase in the Dysanapsis-Ratio (p<0.001). CWS increased airway distensibility at the 6th major branch of the right lower airway (27±7% vs. 39±5%, p=0.04). The dysanapsis-ratio allows quantification of dynamic-dysanapsis with CWS. Dynamic-dysanapsis appears to be a compensatory mechanism to preserve pulmonary gas exchange by airway dilation when the lung is forced to operate at lower lung volumes. Dynamic-dysanapsis furthers the understanding of oversized allografts in lung transplantation.
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