Evidence map›Paper›PMID 40678365›Full record

ArticleJHLT open2025

Fluid management of cardiopulmonary bypass during pulmonary endarterectomy for CTEPH patients impacts perioperative outcome.

K Furrer, D Bettex, T Horisberger, I Inci, N G Nagaraj, H-T Morselli, B Battilana, R Schuepbach, S Ulrich, M Hebeisen and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

K FurrerDepartment of Thoracic Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
D BettexInstitute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland.
T HorisbergerInstitute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland.
I InciDepartment of Thoracic Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
N G NagarajDepartment of Perfusion, University Hospital Zurich, Zurich, Switzerland.
H-T MorselliDepartment of Thoracic Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
B BattilanaDepartment of Thoracic Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
R SchuepbachInstitute of Intensive Care Medicine, University and University Hospital Zurich, Zurich, Switzerland.
S UlrichDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
M HebeisenDepartment of Thoracic Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
I OpitzDepartment of Thoracic Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary endarterectomy (PEA) using deep hypothermic circulatory arrest (DHCA) and cardiopulmonary bypass (CPB) is the preferred treatment for chronic thromboembolic pulmonary hypertension (CTEPH). Crystalloid priming solutions cause hemodilution with disadvantages, and no standard exists for PEA. This study evaluates CTEPH patient outcomes after adding 5% human albumin (HA) to the CPB-prime and hemodilution solution during PEA. Methods: The effect of the CPB-protocol change was evaluated by comparing patients operated under the old and new protocols in a 1:1 propensity score match based on age, sex, and preoperative peripheral vascular resistance (PVR). Results: Matching resulted in 56 patients (28 per group) between July 1, 2010, and May 31, 2020. The new protocol group had a lower intraoperative fluid balance (1.85 vs 6.76 liters, Conclusions: Priming and maintenance protocol for CPB with the addition of 5% HA had a beneficial effect on intraoperative fluid balance and improved outcome after PEA for patients with CTEPH.

Indexed as

5% humanAlbumin (HA) primingCardiopulmonary bypass (CPB)Chronic thromboembolic pulmonary hypertension (CTEPH)Crystalloid priming solutionsPulmonary endarterectomy (PEA)

Identifiers

PMID40678365
PMCPMC12268579

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.