Evidence map›Paper›PMID 40678309›Full record

ReviewCurrent health sciences journal

Burn Debridment - Approach and Review.

Elena Alexandra Marinescu, Alina Andreea Negrilă, Răzvan Alexandru Marinescu, Oliviu Nica, Alexandru Tălăban, Marius Eugen Ciurea, Ana Maria Ciurea

Abstract readReview
In one paragraph

Review in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena Alexandra MarinescuDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania.
Alina Andreea NegrilăPhD Student, Department of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania.
Răzvan Alexandru MarinescuPhD Student, Department of General Surgery, University of Medicine and Pharmacy of Craiova, Romania.
Oliviu NicaDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania.
Alexandru TălăbanDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania.
Marius Eugen CiureaDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania.
Ana Maria CiureaDepartment of Oncology, University of Medicine and Pharmacy of Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Between January 2020 and December 2024, a significant number of burn patients were admitted to the Plastic Surgery Clinic of the Craiova Emergency Clinical Hospital. Due to the high incidence of burns requiring hospitalization and the limited number of beds available for such patients, it became essential to identify optimal treatment methods that could reduce hospital stay while ensuring favorable functional and aesthetic outcomes. Early debridement is considered a vital first step in the treatment of burn patients, ideally performed within the first few days post-injury. Burn treatment involves both surgical and systemic approaches. Surgical management includes debridement, skin grafting, and reconstruction. Tangential surgical debridement remains the gold standard for deep burns, allowing precise removal of necrotic tissue while preserving viable skin. However, it may be associated with disadvantages such as intraoperative blood loss and incomplete excision. Alternative methods have evolved, such as hydrodissection, which uses a high-pressure saline jet for selective debridement, particularly useful in partial thickness burns. Larval therapy (using sterile Lucilia sericata maggots) is another option, especially effective in infected or necrotic wounds, offering antimicrobial benefits as well. Enzymatic debridement, particularly with bromelain-based products, is a modern, selective, and less invasive method that promotes healing with minimal bleeding and often reduces the need for grafting. A clinical case from Craiova highlights the success of enzymatic debridement: a 75-year-old patient with extensive burns showed significant improvement and near-complete epithelialization after 24 days, without requiring grafts. These outcomes support the growing use of enzymatic agents as a valuable tool in modern burn management, offering rapid, effective treatment and better patient recovery.

Indexed as

burnEnzymatic debridementhydrodissectionlarval therapy

Identifiers

PMID40678309
PMCPMC12265004

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.