Evidence map›Paper›PMID 40678250›Full record

ArticleResearch square2025

Sexually-dimorphic neurons in the

David Deutsch, Arie Matsliah, Kaiyu Wang, Sven Dorkenwald, Arpita Mondal, Austin Burke, James Hebditch, Jay Gager, Szi-Chieh Yu, Amy Sterling and 11 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

David DeutschDepartment of Neurobiology, University of Haifa, Haifa, Israel.ORCID 0000-0002-8587-2435
Arie MatsliahPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Kaiyu WangShanghai Center for Brain Science and Brain-Inspired Intelligence Technology, Shanghai, China.
Sven DorkenwaldAllen Institute for Brain Science, Seattle, WA, USA.
Arpita MondalDepartment of Neurobiology, University of Haifa, Haifa, Israel.
Austin BurkePrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
James HebditchPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Jay GagerPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-8001-2604
Szi-Chieh YuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0009-0001-9684-0156
Amy SterlingPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-4961-3954
Claire McKellarPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Philipp SchlegelNeurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0002-5633-1314
Stephan GerhardAware LLC, Rappenstrasse, Effretikon, Switzerland.ORCID 0000-0003-4454-6171
Gabriella SterneUniversity of Rochester Medical Center, Department of Biomedical Genetics, New York, NY USA.ORCID 0000-0002-7221-648X
Marta CostaDrosophila Connectomics Group, Department of Zoology, University of Cambridge, Cambridge, UK.ORCID 0000-0001-5948-3092
Katharina EichlerDrosophila Connectomics Group, Department of Zoology, University of Cambridge, Cambridge, UK.ORCID 0000-0002-7833-8621
Yijie YinDrosophila Connectomics Group, Department of Zoology, University of Cambridge, Cambridge, UK.ORCID 0000-0002-5026-2602
S X E GregoryNeurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0002-0587-9355
Barry DicksonQueensland Brain Institute, University of Queensland, Brisbane, Australia.ORCID 0000-0003-0715-892X
H Sebastian SeungPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-8591-6733
Mala MurthyPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0003-3063-3389

Funding

Dissemination of FlyWire, A Whole-Brain Connectomics ResourceU24NS126935 · NINDS · PRINCETON UNIVERSITY · PI Mala Murthy · 2022 to 2026
$5.6M
Crowdsourcing the Fly ConnectomeRF1MH117815 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA, SEUNG, HYUNJUNE SEBASTIAN · 2018 to 2018
$3.3M
Accelerating connectomic proofreading for larger brains and multiple individualsRF1MH129268 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA · 2022 to 2022
$2.1M
NIMH NIH HHS RF1 MH117815NIMH NIH HHS RF1 MH129268NINDS NIH HHS U24 NS126935Wellcome Trust
6 · The paper itself

Abstract

Sexual dimorphisms are present across brains. Male and female brains contain sets of cell types with differences in cell number, morphology, or synaptic connectivity between the two sexes. These differences are driven by differentially-expressed transcription factors, which set the stage for disparate sexual and social behaviors observed between males and females, such as courtship, aggression, receptivity, and mating. In the

Identifiers

PMID40678250
PMCPMC12270219

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.