ArticleInternational journal of cardiology. Heart & vasculature2025
Long-term left ventricular ejection function in fulminant and non-fulminant myocarditis: A multicenter study in China.
Article in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Highlights recently published in the International Journal of Cardiology Heart & Vasculature on sex differences in susceptibility, manifestation and outcome of cardiovascular diseases.International journal of cardiology. Heart & vasculature · 2026Article
- Evaluation of Prognosis and Risk Factors of Fulminant Myocarditis Complicated with Malignant Arrhythmia.Journal of cardiovascular development and disease · 2025Article
- Beyond the storm: rethinking recovery in fulminant myocarditis.International journal of cardiology. Heart & vasculature · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: There is a gap regarding comparisons of left ventricular ejection fraction (LVEF) changes between fulminant myocarditis (FM) and non-FM (NFM) patients at different follow-up intervals. Methods: This multicenter retrospective study included 324 patients (163 FM and 161 NFM) with confirmed acute myocarditis through endomyocardial biopsy (EMB) or cardiac magnetic resonance imaging. We used multi-model adjustment approach and a mixed-effects model to comprehensively evaluate changes in LVEF in FM relative to NFM, considering both dichotomous outcome (primary outcome) and repeated measurements outcome (secondary outcome). Sensitivity analysis was conducted for patients aged 15 years and older. Results: FM patients exhibited a higher risk of the primary outcome (LVEF < 55 % at the last two follow-up visits) compared to NFM patients, with an odds ratio (OR) of 8.517 (95 % CI, 4.666-16.552; P < 0.001). Following comprehensive adjustment for confounders, the OR for FM versus NFM was 7.438 (95 % CI, 3.967-14.763; P < 0.001). Analysis of repeated measurements (secondary outcome) revealed that LVEF in the NFM group surpassed that in the FM group at different follow-up time points. Consistent findings were observed in the sensitivity analysis population. Additionally, after adjusting for potential confounders, intra-aortic ballon pump (IABP) and extracorporeal membrane oxygenation (ECMO) demonstrated OR values of 0.030 (95 % CI: 0.002-0.197; P = 0.001) and 0.339 (95 % CI: 0.124-0.880; P = 0.030) in patients with FM, respectively. Conclusion: FM patients face a lower LVEF compared to NFM patients across various follow-up intervals. Additionally, early application of IABP and ECMO can enhance long-term LVEF in patients with FM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.