Evidence map›Paper›PMID 40678101›Full record

ArticleBasic and clinical neuroscience2025

Impact of Circadian Rhythm Disturbance and Chronotype on Medical Students' Mental State.

Mohammad Niroumand Sarvandani, Behzad Garmabi, Masoud Asadi, Hamed Ghazvini, Raheleh Rafaiee, Hamid Kalalian Moghaddam

Abstract read
In one paragraph

Article in Basic and clinical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad Niroumand SarvandaniStudent Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.ORCID https://orcid.org/0000-0001-9790-3908
Behzad GarmabiSchool of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.ORCID https://orcid.org/0000-0001-8228-0250
Masoud AsadiDepartment of Psychology, Faculty of Humanities, Arak University, Arak, Iran.ORCID https://orcid.org/0000-0001-5872-7673
Hamed GhazviniPsychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.ORCID https://orcid.org/0000-0002-7644-4834
Raheleh RafaieeDepartment of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran.ORCID https://orcid.org/0000-0003-2796-5868
Hamid Kalalian MoghaddamDepartment of Addiction Studies, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.ORCID https://orcid.org/0000-0002-8342-919X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Shift workers usually undergo circadian misalignment, which appears when the feeding and sleep-wake cycles are desynchronized with the temporal framework organized by the internal biological clock. People differ considerably in their tolerance to shift work depending on their chronotype. This research aimed to obtain information about circadian disorders and chronotype (as a mediating variable) on consequent mental states such as impulsivity, depression, anxiety, stress, addiction potential, and boredom in students of a medical university in northeastern Iran. We studied the mental state of individuals with circadian misalignment and compared it with the healthy control group. Methods: The study design is a double-blind, randomized, controlled clinical trial. Thirty-five participants were randomly assigned to circadian alignment/misalignment protocols. Subjects completed questionnaires as baseline data (pre-test) and the end of the interventions (post-test). The study instruments were the multidimensional state boredom scale (MSBS), addiction potential scale, depression, anxiety, and stress scale-21, and Barratt impulsiveness-11 (BIS-11). To analyze outcomes, we categorized participants based on chronotype as mediate variable within each group (circadian aligned and misaligned condition). Results: The mean age of the participants was 21.66 years (range: 18-25 years). One-way analysis of variance to compare research variables in groups based on chronotype (evening, intermediate type, and morning types) showed a significant difference between the three chronotype groups in the total and non-planning impulsivity, as well as active and passive addiction potential (P<0.001). The Bonferroni post hoc test was used to compare the mean of variables in the chronotype groups about total and non-planning impulsivity scores, as well as active and passive addiction. The results showed that non-planning (P<0.01) and active addiction (P<0.001) in people with evening and intermediate types were significantly lower than in people with morning type (P=0.02). Conclusion: Alterations in diurnal profiles of activity, sleep, and feeding time, based on chronotype related to impulsiveness and boredom, and such circadian misalignment were associated with addiction potential.

Indexed as

AnxietyBoredomChronobiologyCircadian rhythmDepressionStress disordersSubstance-related disorders

Identifiers

PMID40678101
PMCPMC12265443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.