Evidence map›Paper›PMID 40678066›Full record

ArticleFrontiers in oncology2025

Association of cumulative exposure to Chinese visceral adiposity index and gastrointestinal cancer: a prospective cohort study.

Jiaxing Li, Chao Ma, Kuan Liu, Wanchao Wang, Shuqing Cui, Yuan Tian, Zhigang Dong, Wenqiang Wei, Shouling Wu, Siqing Liu

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Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiaxing LiFirst Division of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei, China.
Chao MaFirst Division of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei, China.
Kuan LiuFirst Division of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei, China.
Wanchao WangFirst Division of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei, China.
Shuqing CuiGraduate School, North China University of Science and Technology, Tangshan, Hebei, China.
Yuan TianFirst Division of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei, China.
Zhigang DongFirst Division of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei, China.
Wenqiang WeiFirst Division of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei, China.
Shouling WuHealth Care Center, Affiliated Kailuan General Hospital of North China University of Science and Technology, Tangshan, Hebei, China.
Siqing LiuFirst Division of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Using the Kailuan Cohort, we investigated the association between cumulative exposure to the Chinese visceral adiposity index (CVAI) and the risk of developing gastrointestinal (GI) cancers. Methods: A prospective cohort study was conducted among participants who underwent three consecutive health examinations in the Kailuan Cohort from 2006 to 2010. Participants were categorized into quartiles based on their cumulative CVAI (cumCVAI). The cumulative incidence of GI cancers was estimated using Kaplan-Meier curves. The dose-response relationship between CVAI and the risk of developing GI cancers was examined using restricted cubic spline (RCS) in multivariable adjusted models. Multivariate Cox proportional hazards regression analysis was performed to assess the association between cumCVAI quartiles and the incidence of GI cancers. Furthermore, subgroup analyses and sensitivity analyses were conducted. Results: A total of 44,213 individuals were included in this study. The incidence rates of GI cancers per 1,000 person-years for the Q1 to Q4 groups were 1.00,1.45,1.62 and 2.11, respectively. The RCS curve demonstrated a significant dose-response relationship between cumCVAI and the occurrence of GI cancers events ( Conclusion: Our findings demonstrate a significant association between high cumCVAI and an increased incidence of GI cancers. Prolonged maintenance of CVAI within optimal levels may serve as a potential preventive strategy for GI cancers.

Indexed as

Chinese visceral adiposity indexcohort studygastrointestinal cancervisceral adipose tissuevisceral fat

Identifiers

PMID40678066
PMCPMC12267042

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.