Evidence map›Paper›PMID 40677958›Full record

ReviewLaryngoscope investigative otolaryngology2025

Comparison of Outcomes Between Primary Laryngotracheal Reconstruction and Partial Cricotracheal Resection in Moderate Grade Pediatric Subglottic Stenosis: A Systematic Review and Meta-Analysis.

Bigyan Raj Gyawali, Heempali Dutta, Anuj Devkota, Nitin Gyawali, Sangit Chhantyal, Amit Kumar Mishra, Sanjeev Kharel, Karthik Balakrishnan, Douglas Sidell

Abstract readReview
In one paragraph

Review in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bigyan Raj GyawaliDepartment of ENT and Head Neck Surgery Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.
Heempali DuttaDepartment of ENT and Head Neck Surgery Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.
Anuj DevkotaDepartment of ENT and Head Neck Surgery Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.ORCID https://orcid.org/0000-0001-8188-399X
Nitin GyawaliMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.
Sangit ChhantyalMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.ORCID https://orcid.org/0000-0002-8991-1569
Amit Kumar MishraMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.ORCID https://orcid.org/0000-0002-4574-6215
Sanjeev KharelMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.
Karthik BalakrishnanDepartment of Otolaryngology and Head and Neck Surgery Lucile Packard Children's Hospital, Stanford University Palo Alto California USA.ORCID https://orcid.org/0000-0002-0244-249X
Douglas SidellDepartment of Otolaryngology and Head and Neck Surgery Lucile Packard Children's Hospital, Stanford University Palo Alto California USA.ORCID https://orcid.org/0000-0002-2088-6502

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This systematic review and meta-analysis compare the outcomes of primary laryngotracheal reconstruction (LTR) and partial cricotracheal resection (PCTR) in managing moderate-grade pediatric subglottic stenosis (severe Grade II and Grade III). While both surgical approaches are widely used, no clear consensus exists on the superior technique. Methods: A systematic literature search was conducted across PubMed, Embase, and Scopus following PRISMA guidelines. Studies reporting outcomes of LTR and PCTR in pediatric patients (< 18 years) with severe Grade II (> 60%) or Grade III subglottic stenosis were included. The primary outcome was successful extubation or decannulation. Statistical analysis, including pooled prevalence estimates and heterogeneity assessment, was performed using STATA software. Results: A total of 24 studies were included, comprising 193 patients in the LTR group and 88 in the PCTR group. Successful decannulation was achieved in 83.93% of LTR cases and 96.59% of PCTR cases. However, the difference was not statistically significant ( Conclusion: Both LTR and PCTR are viable options for moderate-grade pediatric subglottic stenosis, with comparable decannulation success rates. PCTR may offer advantages in functional outcomes, but further research with standardized reporting is necessary to establish an optimal surgical approach. Level of Evidence: II.

Indexed as

airway surgerylaryngotracheal reconstructionmeta‐analysispartial cricotracheal resectionpediatric subglottic stenosis

Identifiers

PMID40677958
PMCPMC12267102

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.