ArticleBiomedical optics express2025
Asymmetric activation of retinal ON and OFF pathways by AOSLO raster-scanned visual stimuli.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Phase diversity improves retinal image quality in adaptive optics scanning light ophthalmoscopy.Biomedical optics express · 2026Article
- Sub-cone visual acuity can be achieved with less than 1 arcmin retinal slip.Journal of vision · 2026Article
- Phase diversity improves retinal image quality in adaptive optics scanning light ophthalmoscopy.bioRxiv : the preprint server for biology · 2025Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Adaptive optics scanning light ophthalmoscopy (AOSLO) enables high-resolution retinal imaging, eye tracking, and stimulus delivery in the living eye. AOSLO-mediated visual stimuli are created by temporally modulating the excitation light as it scans across the retina. As a result, each location within the field of view receives a brief flash of light during each scanner cycle (every 33-40 ms). Here, we used in vivo calcium imaging with AOSLO to investigate the impact of this intermittent stimulation on the retinal ON and OFF pathways. Raster-scanning exaggerated existing ON-OFF pathway asymmetries at high light levels, leading to high baseline activity in ON cells and increased rectification in OFF cells.
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