ArticleBiomedical optics express2025
Temporally delayed, dual-pulse, dual-wavelength photoacoustic imaging (TD-DP-DW-PAI): advancing capabilities of a commercial light-emitting diode-based photoacoustic imaging system with a pulsed laser diode.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Introduction to the feature issue Photoacoustic Imaging and Sensing: Beyond Fundamentals to Translation.Biomedical optics express · 2026Article
- Near-infrared-II pulsed laser diode array for spectral photoacoustic imaging of deep tissue oxygenation.Biomedical optics express · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photoacoustic imaging (PAI) is a hybrid imaging technique providing optical contrast with ultrasound resolution for deep tissue imaging. Typical light sources used for PAI include pulsed lasers, pulsed laser diode (PLD), and light-emitting diodes (LED). LED is the most economical light source among these, and there are commercial photoacoustic + ultrasound imaging (PAUS) systems with LED-based light illumination. However, LEDs have low energy per pulse compared to pulsed lasers and PLDs, leading to limited applications. Therefore, in this work, we demonstrate temporally delayed, dual-pulse, dual-wavelength photoacoustic imaging (TD-DP-DW-PAI) using an additional PLD illumination to enhance the performance and functionality of a commercial LED-based PAUS system. Three key improvements were demonstrated with phantom imaging - image quality enhancement, imaging frame rate enhancement, and functional imaging enhancement (multispectral imaging) without compromising the frame rate. We demonstrated signal-to-noise improvement by a factor of two, non-linear doubling of the frame rate, and multi-wavelength imaging without compromising the LED's low energy illumination and frame rate.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.