ArticleBiomedical optics express2025
Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- First-order field autocorrelation function analysis-based dynamic OCT for tissue viability assessment.Biomedical optics express · 2026Article
- Dynamic full-field swept-source optical coherence tomography for high-resolution, long-depth, and intratissue-activity imaging.Biomedical optics express · 2026Article
- Dynamic optical coherence microscope integrated with cell-cultivation chamber enabled longitudinal and early-stage assessment of tumor spheroid-drug interaction.Scientific reports · 2026Article
- Longitudinal investigation of prostate tumor spheroid proliferation with dynamic line-field optical coherence tomography.Biomedical optics express · 2026Article
- Imaging of Tissue and Cell Dynamics: introduction to the feature issue.Biomedical optics express · 2026Article
- Dynamic optical coherence tomography algorithm for label-free assessment of swiftness and occupancy of intratissue moving scatterers.Biomedical optics express · 2026Article
- Review of dynamic optical coherence tomography for intracellular motility: signals, metrics, and their applications [Invited].Biomedical optics express · 2025Review
- Guide to dynamic OCT data analysis.Biomedical optics express · 2025Article
- Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals.Biomedical optics express · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dynamic optical coherence tomography (DOCT) enables label-free functional imaging by capturing temporal OCT signal variations caused by intracellular and intratissue motions. However, the relationship between DOCT signals and the sample motion behind them remains unclear. This paper presents a comprehensive DOCT simulation framework that incorporates mathematical models of intracellular/intratissue motions, two OCT signal generator types that generate OCT signal time sequences from the moving scatterer models, and representative DOCT algorithms. The theory and algorithms of the framework are described in detail, and the utility of this framework is demonstrated through numerical studies. This framework is available as open source and will enhance the understanding and utility of DOCT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.