ArticleOsteoporosis and sarcopenia2025
Fracture risk in Korean postmenopausal women: The influence of BMI, age, and bone density.
Article in Osteoporosis and sarcopenia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Fracture risk in postmenopausal women is influenced by bone mineral density (BMD), age, and body mass index (BMI). However, fracture prevention strategies primarily focus on low BMD, often overlooking other key factors. Methods: This retrospective cohort study analyzed 18,151 Korean postmenopausal women aged 50 or older who underwent dual-energy X-ray absorptiometry (DXA) at Ajou University Hospital from years of 2006-2014. Fracture risk was assessed using multivariable Cox proportional hazard models, adjusted for BMI, BMD, and age. Results: The median age of the cohort was 59.1 years, and the overall fracture incidence was 2.3 per 1,000 person-years. Fracture risk significantly increased with age, with hazard ratios (HRs) of 1.36 (95% CI: 1.08-1.70) for women aged 60-69 and 2.10% (95% CI: 1.62-2.73) for those aged 70 or older, compared to the reference group (50-59 years). Underweight women exhibited the highest fracture cumulative incidence (3.3%), though their risk increase was not statistically significant. Overweight and obese women demonstrated higher BMD but did not show significant fracture risk reductions. Conclusions: These findings highlight age as a dominant predictor of fracture risk, while BMI plays a complex, less pronounced role. The discrepancy between osteoporosis prevalence and actual fracture risk, particularly in obese elderly women, suggests limitations in BMD-focused assessments. Simple, measurable parameters like age and BMI should complement BMD in fracture risk evaluation to better target high-risk populations and enhance preventive strategies in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.