ArticleFrontiers in surgery2025
Clinical outcomes of tibial nonunion treatment through the combination of PRP, autogenous iliac bone grafting, and augmentation plating.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Case Report: Management of tibial fracture nonunion: a case study of treatment failure and lessons learned.Frontiers in surgery · 2026Article
- Recent Advancements in Non-surgical Approaches for the Management of Delayed Union and Nonunion in Long Bone Fractures of the Extremities: A Review.Advances in therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To explore the clinical efficacy of PRP (Platelet-Rich Plasma), autogenous bone combined with augmentation plating in the treatment of tibial nonunion. Methods: A total of 45 patients with tibial nonunion who fulfilled the inclusion criteria were meticulously selected and subsequently randomized into three distinct groups: Group A, which received PRP, autogenous bone grafting, and augmentation plating; Group B, which underwent autogenous bone grafting and augmentation plating; and Group C, which only received autogenous bone grafting. Each group comprised 15 patients. Detailed records were maintained for gender, age, BMI (Body Mass Index) as general information, surgery duration, blood loss, length of hospital stay, fracture healing time, and the Fernadez-Esteve score at three specific time points. Results: No statistically significant differences were observed in the general demographic data, including gender, age, and BMI, among the three groups ( Conclusion: PRP, autogenous bone combined with augmentation plating in the treatment of tibial nonunion can promote fracture healing and repair, improve fracture healing rate, and the clinical effect is significant.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.