Evidence map›Paper›PMID 40677601›Full record

ArticleLearning health systems2025

A learning health system model for addressing substance use: Denver Health Center for Addiction Medicine.

Emily Bacon, Laura J Podewils, Brooke Bender, Joshua Blum, Christian Thurstone, Alia Al-Tayyib, John Mills, Alexandra R Tillman, Judith Shlay

Abstract read
In one paragraph

Article in Learning health systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emily BaconDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.ORCID https://orcid.org/0000-0001-6197-1650
Laura J PodewilsDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.
Brooke BenderDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.
Joshua BlumDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.
Christian ThurstoneDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.
Alia Al-TayyibDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.
John MillsDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.
Alexandra R TillmanDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.ORCID https://orcid.org/0000-0001-5699-6466
Judith ShlayDenver Health and Hospital Authority Center for Addiction Medicine Denver Colorado USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Substance use disorders (SUDs) continue to place heavy burdens on patients, health systems, and communities. Rapidly evolving treatment for SUDs requires health systems that can efficiently and effectively assess data and integrate evidence to practice. This paper describes the implementation of a learning health systems model of SUD care at an urban, safety-net, integrated health system in Denver, Colorado. Methods: The health system created the Center for Addiction Medicine (CAM) to coordinate comprehensive services for patients with SUD, including research, evaluation, and quality improvement efforts. CAM implemented a hub-and-spoke model of care and developed four strategic areas to identify, integrate, and grow SUD services. CAM also created a process for engaging community members with lived experience with SUDs and a CAM Academy to educate partners within the health system and across the region. Results: CAM successfully implemented processes for gathering and assessing evidence, informing clinical practice, fostering community partnerships, and strategically expanding services and reach. Key factors driving success include strategic planning, leadership buy-in, data infrastructure, and community partnerships. Conclusions: Integrated SUD care at a safety-net institution is a continued challenge. Persistent barriers include the SUD policy and regulatory landscape, addressing co-occurring social and health circumstances when treating SUDs, and accurate clinical documentation of SUDs. Applying a learning health system model can help health systems adapt to these challenges.

Indexed as

implementation sciencelearning health systemopioid use disorderquality improvementsubstance use

Identifiers

PMID40677601
PMCPMC12264389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.