Evidence map›Paper›PMID 40677578›Full record

ArticleWorld journal of gastrointestinal endoscopy2025

Diagnostic yield of video capsule endoscopy

Eyad Gadour, Bogdan Miutescu, Hussein Hassan Okasha, Ana Maria Ghiuchici, Mohammed S AlQahtani

Abstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eyad GadourMultiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.
Bogdan MiutescuDepartment of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara 300041, Romania.
Hussein Hassan OkashaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Kasr Al-Aini School of Medicine, Cairo University, Cairo 11562, Egypt.
Ana Maria GhiuchiciDepartment of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara 300041, Romania.
Mohammed S AlQahtaniMultiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmall-bowel disorders, including obscure gastrointestinal bleeding (OGIB), Crohn's disease, and tumors, require accurate diagnostic approaches for effective treatment. Video capsule endoscopy (VCE) and simple balloon enteroscopy (SBE) are widely used; however, each modality has limitations, particularly regarding therapeutic intervention and diagnostic yield.

aimTo evaluate diagnostic yields of various modalities for small bowel bleeding, analyze factors affecting heterogeneity, and improve understanding of clinical outcomes associated with different diagnostic approaches.

methodsA comprehensive search of four databases (PubMed, Embase, Cochrane Library, and Scopus) revealed over 600 citations related to the use of capsule endoscopy and balloon enteroscopy for diagnosing small intestine disorders with wall thickening. Based on predetermined eligibility criteria, seven moderate-to-high-quality retrospective studies were analyzed to evaluate the diagnostic performance of VCE and SBE in patients with small bowel disorders. Quality Assessment of Diagnostic Accuracy Studies was applied to evaluate the risk of bias and overall methodological quality.

resultsAnalysis of seven moderate-to-high-quality retrospective studies revealed comparable overall detection rates for small bowel lesions between VCE and SBE. VCE demonstrated superior performance in detecting vascular lesions. Conversely, SBE exhibited a higher efficacy in detecting ulcerative lesions. The overall diagnostic yield varied across studies, with VCE showing a range of 32%-83% for small bowel bleeding, whereas SBE demonstrated a higher overall detection rate of 69.7% compared to 57.6% for VCE (

conclusionVCE and SBE are complementary techniques for evaluating small intestinal disorders. Although VCE remains the initial test of choice for patients with stable OGIB, SBE should be considered in patients requiring therapeutic intervention. Thus, combining both modalities enhances diagnostic accuracy and patient management.

Indexed as

Diagnostic yieldObscure gastrointestinal bleedingSingle balloon enteroscopySmall intestine disordersVideo capsule endoscopy

Identifiers

PMID40677578
PMCPMC12264748

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.