Evidence map›Paper›PMID 40677565›Full record

ArticleWorld journal of gastrointestinal endoscopy2025

Evolving role of endoscopic ultrasound in biliary stricture management: A meta-analysis and systematic review.

Eyad Gadour, Bogdan Miutescu, Hussein H Okasha, Mohammed Albeshir, Turki Alamri, Elsayed Ghoneem, Călin Burciu, Alexandru Popa, Oana Koppandi, Mohammed S AlQahtani

Abstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eyad GadourMultiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.
Bogdan MiutescuDepartment of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara 300041, Romania.
Hussein H OkashaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Kasr Al-Aini School of Medicine, Cairo University, Cairo 11562, Egypt.
Mohammed AlbeshirDivision of Gastroenterology, Department of Medicine, King Fahad Specialist Hospital, Dammam 32252, Saudi Arabia.
Turki AlamriDepartment of Internal Medicine, Gastroenterology Unit, King Fahad University Hospital, Al Khobar 32252, Saudi Arabia.
Elsayed GhoneemDivision of Gastroenterology, Department of Medicine, King Fahad Specialist Hospital, Dammam 32252, Saudi Arabia.
Călin BurciuDepartment of Gastroenterology, Faculty of Medicine, Pharmacy and Dental Medicine, "Vasile Goldis" West University of Arad, Arad 310414, Romania.
Alexandru PopaAdvanced Regional Research Center in Gastroenterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.
Oana KoppandiDepartment of Gastroenterology, Faculty of Medicine, Pharmacy and Dental Medicine, "Vasile Goldis" West University of Arad, Arad 310414, Romania.
Mohammed S AlQahtaniMultiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic ultrasound (EUS) has evolved from a diagnostic tool to a management technique for various gastroenterological conditions, including biliary strictures.

aimTo summarize the current evidence on EUS's role in diagnosing and managing biliary strictures.

methodsTwo independent reviewers searched five electronic databases (PubMed, CENTRAL, Science Direct, Google Scholar, and EMBASE) for articles published up to January 2025. Included articles met specific criteria, and statistical software was used to analyze reported outcomes.

resultsOf 935 articles, 19 met the inclusion criteria. Ten articles focused on diagnostic EUS, while nine focused on EUS-guided therapeutic interventions. EUS fine-needle aspiration demonstrated superior sensitivity [0.43-1.00; 95% confidence interval (CI): 0.24-1.00] compared to conventional techniques (0.36-0.96; 95%CI: 0.19-0.99) for diagnosing malignant biliary strictures. Both EUS-fine-needle aspiration and conventional methods exhibited high specificity, with most achieving 100% specificity. EUS-guided interventions showed significantly higher clinical success rates than control interventions (odds ratio = 2.89; 95%CI: 1.22-6.84;

conclusionEUS is a promising tool for diagnosing and managing biliary strictures. Combining EUS-guided and conventional interventions improves diagnostic performance. Further research is needed to investigate the feasibility and use of EUS-guided interventions in this field.

Indexed as

Biliary stricturesClinical success rateEndoscopic ultrasoundEndoscopic ultrasound guided fine-needle aspirationSystematic review

Identifiers

PMID40677565
PMCPMC12264785

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.