Evidence map›Paper›PMID 40677523›Full record

ArticleFrontiers in cellular and infection microbiology2025

Bacterial profiling of colorectal cancer biopsies: a culture-based study in Indian patients.

Manish Kushwaha, Shubham Chaudhary, Akhilesh Kumar Singh, Govind K Makharia, Anil Kumar

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manish KushwahaGene Regulation Laboratory, National Institute of Immunology, New Delhi, India.
Shubham ChaudharyDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
Akhilesh Kumar SinghSchool of Life Sciences, Department of Biotechnology, Mahatma Gandhi Central University, Motihari, Bihar, India.
Govind K MakhariaDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
Anil KumarGene Regulation Laboratory, National Institute of Immunology, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging research has highlighted the significant role of microorganisms in the initiation and progression of colorectal cancer (CRC). However, further investigation is required to elucidate the precise mechanisms by which the microbial community or specific bacteria contribute to carcinogenesis. The present work deals with the isolation and identification of bacteria from nine CRC biopsy samples and nine adjacent normal biopsy samples. Different media, such as brain heart infusion (BHI), anaerobic basal agar (ABA), and trypticase soy agar (TSA), and culture conditions have been manipulated to maximize the isolation of bacteria residing in biopsy samples. A total of 75 bacteria were isolated from the tumor and adjacent site.

Indexed as

BacteriaColorectal NeoplasmsAgedBacteriological TechniquesBiopsyCulture MediaFemaleHumansIndiaMaleMiddle AgedCulture Mediabacterial diversitycarcinogenesiscolorectal cancerculturomicsgut microbiota

Identifiers

PMID40677523
PMCPMC12267230

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.