Evidence map›Paper›PMID 40677506›Full record

ArticleCureus2025

Unraveling the Yellow Mystery: Severe Jaundice and Multisystem Collapse in a Returning Traveler.

Bharadwaj Adithya Sateesh, Natalie Shammas, Ahmed Abdelfattah, Jarmil Alyssa Peters, Kristin Dishongh, Ashley Jenkins, John Mark P Pabona

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bharadwaj Adithya SateeshInternal Medicine, Catholic Health Initiatives (CHI) St. Vincent, Hot Springs, USA.
Natalie ShammasInternal Medicine, Catholic Health Initiatives (CHI) St. Vincent, Hot Springs, USA.
Ahmed AbdelfattahInternal Medicine, Catholic Health Initiatives (CHI) St. Vincent, Hot Springs, USA.
Jarmil Alyssa PetersPulmonary and Critical Care Medicine, Catholic Health Initiatives (CHI) St. Vincent, Hot Springs, USA.
Kristin DishonghPathology, Catholic Health Initiatives (CHI) St. Vincent, Hot Springs, USA.
Ashley JenkinsInternal Medicine, Catholic Health Initiatives (CHI) St. Vincent, Hot Springs, USA.
John Mark P PabonaInternal Medicine, Catholic Health Initiatives (CHI) St. Vincent, Hot Springs, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 43-year-old male with recent travel history and possible toxic exposure abroad who was admitted with altered mental status following a seizure. His course was complicated by multiorgan dysfunction, including acute renal failure, rhabdomyolysis, acute pancreatitis, disseminated intravascular coagulation, and severe jaundice. Extensive infectious and autoimmune workup was unrevealing. Imaging revealed hepatosplenomegaly, hemorrhagic ascites, and progressive pancreatic inflammation. Liver biopsy demonstrated cirrhosis with cholestasis, ballooning degeneration, Mallory hyaline, and bridging fibrosis. Despite supportive care, the patient developed hemorrhagic pancreatitis with retroperitoneal gas, concerning for pancreatic gas gangrene. Surgical intervention was not feasible, and the patient ultimately succumbed to his illness. This case underscores the diagnostic complexity and rapidly fatal potential of overlapping hepatic and pancreatic pathologies in the setting of unclear toxic or environmental exposures.

Indexed as

abdominal gas gangreneacute edematous pancreatitiscirrhosisedematous pancreatitisgas gangrenejaundiceshock

Identifiers

PMID40677506
PMCPMC12269799

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.