ArticleCureus2025
Clinical Case of a 20-Year-Old Man With Myeloneuropathy Due to Vitamin B12 Deficiency From Nitrous Oxide Abuse: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Vitamin B12 deficiency-associated myeloneuropathy is a combination of subacute combined degeneration of the spinal cord and peripheral neuropathy. There are various causes of vitamin B12 deficiency, including diet mistakes, gastrointestinal diseases, genetic disorders, and medication intake. We present a clinical case of a 20-year-old male with myeloneuropathy due to vitamin B12 deficiency. The symptoms had been developing for four to five months, and upon admission to our clinic, the patient was presented with superficial and deep sensation deficit, distal paresthesia, muscle weakness, spastic-paretic gait, and the feeling of incomplete emptying of the bladder after urinating. The MRI revealed hyperintense lesions in cervical and thoracic areas of the spinal cord, and the electroneurogram indicated decreased conduction speed and severe axonal damage of the peripheral nerves. The patient admitted about transitional abdominal pain for years and chronic overuse of nitrous oxide (
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