ArticleCureus2025
Investigating the Outcomes and Complications of Urethroplasty Using Different Graft Materials in Men With Complex or Recurrent Urethral Strictures.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Penile skin graft versus buccal mucosal graft for anterior urethral strictures in adult urethroplasty- a systematic review and meta-analysis.International urology and nephrology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Complex and recurrent urethral strictures present significant surgical challenges, with graft-based urethroplasty being the mainstay of treatment. Optimal graft selection remains controversial, particularly between buccal mucosa and penile skin grafts. Objective To compare clinical outcomes, complication rates, and patient-reported satisfaction following urethroplasty using buccal mucosa versus penile skin grafts. Methods This retrospective cohort study was conducted at Nishtar Hospital, Multan, Pakistan, from January 2022 to December 2024. A total of 178 male patients who underwent substitution urethroplasty were included in the study. Data were retrospectively extracted from electronic medical records and surgical logs. Collected variables included patient demographics (age, comorbid conditions like diabetes or smoking status), stricture characteristics (location, length, etiology, previous treatments), surgical details (graft type, operative time, perioperative complications), and postoperative outcomes. Data were analyzed using SPSS Version 26.0 (IBM SPSS Statistics for Windows, IBM Corp., Armonk, NY). Continuous variables were compared using t-tests and categorical variables using chi-square tests, with p < 0.05 considered statistically significant. Results Surgical success rates were higher in the buccal mucosa group at both 12 months (91 (87.5%) vs. 59 (80.2%)) and 24 months (88 (84.6%) vs. 56 (75.6%)), though differences were not statistically significant. Stricture recurrence and graft contracture were lower in the buccal mucosa group (11 (10.6%) vs. 14 (18.9%)) and (four (3.8%) vs. eight (10.8%)), respectively. International Prostate Symptom Score (IPSS) improvement was significantly greater with buccal mucosa grafts (p = 0.04), and patient satisfaction rates were also higher. Complication rates were low in both groups, but oral donor site morbidity was observed in 19 (18%) of buccal mucosa patients. Conclusions It is concluded that buccal mucosa grafts offer superior functional outcomes, lower complication rates, and greater patient satisfaction compared to penile skin grafts in the setting of complex or recurrent urethral strictures. Buccal mucosa should be considered the preferred graft material when feasible.
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