Evidence map›Paper›PMID 40677452›Full record

ArticleCureus2025

Giant Cell Arteritis With Atypical Features: Acute Vision Loss and Marked Eosinophilia Mimicking Systemic Vasculitis.

David Phrathep, Sabrina A Billings, Hamaad Khan, Palak Patel, Michael Mohseni

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David PhrathepPhysical Medicine and Rehabilitation, Mayo Clinic, Jacksonville, USA.
Sabrina A BillingsInternal Medicine, Mayo Clinic, Jacksonville, USA.
Hamaad KhanPhysical Medicine and Rehabilitation, Mayo Clinic, Jacksonville, USA.
Palak PatelFamily Medicine, Mayo Clinic, Jacksonville, USA.
Michael MohseniEmergency Medicine, Mayo Clinic, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant cell arteritis (GCA), also known as temporal arteritis, is a chronic inflammatory vasculitis that affects the large- and medium-sized arteries, which commonly includes the cranial branches of the carotid arteries. Manifestations range from constitutional symptoms, headache, and jaw claudication to transient or permanent monocular vision loss. Because its prognosis is poor if untreated, patients require prompt evaluation and appropriate treatment. We present an atypical case of binocular vision loss in a patient diagnosed with GCA with eosinophilic granulomatosis with polyangiitis. The patient declined a temporal artery biopsy and opted for ultrasonography, which helped clinch the ultimate diagnosis. His symptoms partially improved with high-dose steroids and tocilizumab in the hospital. Our case highlights the diagnostic challenges, appropriate specialist consultations required, and prompt management of GCA with overlapping vasculitis symptoms.

Indexed as

emergency medicinegiant cell arteritisseronegative eosinophilic granulomatosis with polyangiitistemporal arteritisultrasonographyvasculitisvision loss

Identifiers

PMID40677452
PMCPMC12268962

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.