Evidence map›Paper›PMID 40677447›Full record

ArticleCureus2025

A Rare Collision in Thyroid and Lymph Node: A Case Report and Review of Literature.

Gowtham K V, Suhaildeen Kajamohideen, Arthi M, Leena D Joseph, Ilango Parthasarathy

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gowtham K VSurgical Oncology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Suhaildeen KajamohideenSurgical Oncology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Arthi MPathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Leena D JosephPathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Ilango ParthasarathySurgical Oncology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synchronous papillary and medullary thyroid carcinomas are exceptionally rare. This case report describes a 13-year-old girl with familial medullary thyroid cancer linked to germline rearranged during transfection (RET) proto-oncogene mutation, with a high risk of early onset and aggressive disease, who underwent total thyroidectomy with prophylactic neck dissection. Histopathology revealed distinct papillary and medullary thyroid cancers in separate thyroid lobes, which was a type IV synchronous tumor, with one lymph node showing metastatic deposits from both tumors. This case highlights the rare occurrence, diagnostic challenges of such dual malignancies, emphasizing the need for genetic testing and vigilant long-term follow-up.

Indexed as

braf mutationcarcinoembryonic antigenfamilial medullary thyroid cancermedullary thyroid carcinomamen syndromepapillary thyroid carcinomaret protooncogeneserum calcitoninsynchronous tumors

Identifiers

PMID40677447
PMCPMC12268773

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.