Evidence map›Paper›PMID 40677389›Full record

ArticleBiomedical optics express2025

Label-free sensing technology of two Staphylococcus species based on a terahertz metasurface.

Hui Zhong, Jingle Li, Jinghao Jiang, Xunpei Xu, Dongdong Zhang, Liwei Song, Rui Gao, Ye Tian

Abstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hui ZhongState Key Laboratory of Ultra-intense Laser Science and Technology, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China.
Jingle LiState Key Laboratory of Ultra-intense Laser Science and Technology, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China.
Jinghao JiangDepartment of Orthopedics, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Xunpei XuDepartment of Orthopedics, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Dongdong ZhangState Key Laboratory of Ultra-intense Laser Science and Technology, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China.ORCID https://orcid.org/0000-0001-8627-7016
Liwei SongState Key Laboratory of Ultra-intense Laser Science and Technology, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China.ORCID https://orcid.org/0000-0002-0538-3472
Rui GaoDepartment of Orthopedics, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Ye TianState Key Laboratory of Ultra-intense Laser Science and Technology, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China.ORCID https://orcid.org/0000-0002-5618-5951

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcus epidermidis (SE) and Staphylococcus aureus (SAU), comprising 50% of pathogenic bacteria in clinical blood isolates, demand precise detection for infection control. We present a label-free terahertz (THz) metasurface biosensor enabling simultaneous quantification and speciation of these Gram-positive pathogens. A tailored metasurface enhances THz wave-bacteria interaction through sharp resonance, creating quantitative correlations between resonance shifts and bacterial fluid dosage. Distinct linear regression slopes (SAU: 105.90 GHz/μL, SE: 45.14 GHz/μL) permit species differentiation, achieving specificity without biochemical labeling. This platform eliminates complex surface functionalization, reducing preparation time compared to ELISA-based methods while maintaining high sensitivity (theoretically 135.1 GHz/RIU, at a thickness of 3 μm, and experimentally 556 GHz/cell μm

Identifiers

PMID40677389
PMCPMC12265503

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.