ArticleBiomedical optics express2025
Label-free sensing technology of two Staphylococcus species based on a terahertz metasurface.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Research Progress of Terahertz Technology in Microbiology.Biosensors · 2026Review
- Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Staphylococcus epidermidis (SE) and Staphylococcus aureus (SAU), comprising 50% of pathogenic bacteria in clinical blood isolates, demand precise detection for infection control. We present a label-free terahertz (THz) metasurface biosensor enabling simultaneous quantification and speciation of these Gram-positive pathogens. A tailored metasurface enhances THz wave-bacteria interaction through sharp resonance, creating quantitative correlations between resonance shifts and bacterial fluid dosage. Distinct linear regression slopes (SAU: 105.90 GHz/μL, SE: 45.14 GHz/μL) permit species differentiation, achieving specificity without biochemical labeling. This platform eliminates complex surface functionalization, reducing preparation time compared to ELISA-based methods while maintaining high sensitivity (theoretically 135.1 GHz/RIU, at a thickness of 3 μm, and experimentally 556 GHz/cell μm
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Registered trials
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