ArticleKidney international reports2025
Randomized Double-Blind Placebo-Controlled Trial of Desmopressin for Post-Kidney Biopsy Bleeding.
Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effect of Preprocedural Desmopressin on Complications after Kidney Biopsy: A Systematic Review and Meta-Analysis.Kidney360 · 2026Pooled it
- Efficacy of desmopressin in reducing post-procedural bleeding among chronic kidney disease patients: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Desmopressin and bleeding risk in high-risk native kidney biopsy: updated meta-analysis of RCTs and observational studies.Renal failure · 2025Pooled it
- Effect of desmopressin on bleeding outcomes after native renal biopsy: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Percutaneous Kidney Biopsy: Indications, Technique, and Peri-Procedural Management-A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Nephrologist-led fluoroscopic PD catheter insertion enables safe urgent-start PD: five-year single-center experience.BMC nephrology · 2026Article
- Bleeding prevention with desmopressin for allograft kidney biopsies: a double-blind randomized study.Clinical kidney journal · 2026Article
- Hematuria Management in Patients on Antiplatelet Medications After Acute Coronary Syndrome: A Review of the Current Evidence and Recommendations.Reviews in cardiovascular medicine · 2026Review
- Response to the Letter to the Editor Entitled "Desmopressin After Kidney Biopsy: Are the Risks Worth it?"Kidney international reports · 2025Article
- Desmopressin After Kidney Biopsy: Are the Risks Worth it?Kidney international reports · 2025Article
- Article
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This study evaluated the efficacy and safety of desmopressin in reducing postbiopsy bleeding in patients undergoing kidney biopsy, a common complication requiring effective prevention strategies. Methods: In this double-blind, randomized, placebo-controlled trial conducted from February 2019 to January 2023 at a teaching institute in Lucknow, India, 203 patients aged 18 to 65 years undergoing indication kidney biopsy were randomized to receive desmopressin (300 μg) or placebo intranasally an hour before the procedure. Outcomes included postbiopsy bleeding (primary) and hemoglobin drop, hypotension, hematuria, hematoma, transfusion need, and radiological or surgical interventions (secondary). Results: Bleeding incidence was significantly lower in the desmopressin group (11.9%) compared with placebo (33.3%, Conclusion: Desmopressin effectively reduces postbiopsy bleeding and hematoma formation with manageable side effects, supporting its role as a prophylactic option in kidney biopsies. Further studies are needed to confirm its broader clinical applications.
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